Meta-Analysis
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jul 15, 2025; 16(7): 108121
Published online Jul 15, 2025. doi: 10.4239/wjd.v16.i7.108121
Intervention effect of combined resistance and aerobic exercise on type 2 diabetes: A meta-analysis
Jiang-Chen Ma, Song Shu, Tian-Xiao Chen, Hui-Jing Bai, Ya Yang, Xiao-Wei Ding
Jiang-Chen Ma, Department of Geriatrics, The Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China
Jiang-Chen Ma, Department of Geriatrics, Hangzhou Geriatric Hospital, Hangzhou 310000, Zhejiang Province, China
Song Shu, Xiao-Wei Ding, Department of Rehabilitation Medicine, Hangzhou Geriatric Hospital, Hangzhou 310000, Zhejiang Province, China
Tian-Xiao Chen, Department of Rehabilitation Medicine, The Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China
Hui-Jing Bai, Department of Nutrition, Huadong Hospital, Fudan University, Shanghai 200040, China
Ya Yang, Department of Geriatrics, The Affiliated Huai’an Hospital of Xuzhou Medical University, Huai’an 223003, Jiangsu Province, China
Xiao-Wei Ding, Department of Rehabilitation Medicine, The Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou 310088, Zhejiang Province, China
Co-first authors: Jiang-Chen Ma and Song Shu.
Author contributions: Ma JC and Shu S designed the research; Ma JC, Shu S and Chen TX performed the research and contributed to the methodology; Ma JC, and Bai HJ contributed new reagents or analytic tools; Bai HJ, and Yang Y analyzed the data; Ma JC, Shu S, and Ding XW wrote the paper; Ma JC and Shu S equally contributed to this work as co-first authors; Ding XW reviewed and edited the manuscript.
Supported by Research Project of Zhejiang Provincial Science and Technology Plan for Traditional Chinese Medicine, No. 2024ZL753; and Research Project of Zhejiang Provincial Medical and Health Science and Technology Plan, No. 2024KY1406.
Conflict-of-interest statement: The authors declare that they have no competing interests.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Wei Ding, MD, Director, Department of Rehabilitation Medicine, The Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, No. 88 Bolang Street, Xiasha Street, Qiantang District, Hangzhou 310088, Zhejiang Province, China. 13758120616@163.com
Received: April 15, 2025
Revised: May 19, 2025
Accepted: June 23, 2025
Published online: July 15, 2025
Processing time: 90 Days and 23.5 Hours
Core Tip

Core Tip: Combined resistance and aerobic exercise significantly improves glycemic control and metabolic indicators in patients with type 2 diabetes, including fasting blood glucose, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, and total cholesterol levels. Although no significant improvement was observed in glycated hemoglobin A1c levels, combined exercise remains a promising therapeutic strategy for diabetes management.