Case Control Study
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World J Diabetes. Feb 15, 2025; 16(2): 95102
Published online Feb 15, 2025. doi: 10.4239/wjd.v16.i2.95102
Distinguishing exocrine pancreas disease-associated diabetes from type 2 diabetes based on anthropometric and metabolic parameters
Anna Juza, Lilianna Kołodziej-Spirodek, Krzysztof Gutkowski, Mariusz Partyka, Mariusz Dąbrowski
Anna Juza, Krzysztof Gutkowski, Mariusz Partyka, Mariusz Dąbrowski, College of Medical Sciences, Institute of Medical Sciences, University of Rzeszów, Rzeszów 35-959, Poland
Anna Juza, Lilianna Kołodziej-Spirodek, Diabetic Outpatient Clinic & Department of Gastroenterology and Hepatology with the Subunit of Internal Diseases, University Clinical Hospital, Rzeszów 35-055, Poland
Mariusz Partyka, Department of Internal Diseases, Nephrology and Endocrinology with the Nuclear Medicine Laboratory and the Dialysis Center & Endocrinology Outpatient Clinic, Clinical Provincial Hospital No. 2 in Rzeszów, Rzeszów 35-301, Poland
Author contributions: Gutkowski K, Partyka M, Juza A and Kołodziej-Spirodek L contributed to conceptualization and study design; Juza A and Kołodziej-Spirodek L contributed to data collection; Dąbrowski M contributed to statistical analysis and data interpretation; Juza A, Kołodziej-Spirodek L, Gutkowski K, and Partyka M contributed to data analysis; Juza A and Dąbrowski M contributed to manuscript drafting; all authors contributed to the intellectual content of the manuscript and provided approval of the final version to be published.
Institutional review board statement: The Bioethics Committee at the Regional Medical Chamber in Rzeszów, Poland provided approval for this study (Resolution No. 57/B/2015 issued on 26th June, 2015).
Informed consent statement: Each participant received information about the purpose of the study and signed an informed consent form before starting the procedures related to participation in the study.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: data are deposited at the University of Rzeszów repository: https://repozytorium.ur.edu.pl/handle/item/8589.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mariusz Dąbrowski, MD, PhD, Adjunct Associate Professor, College of Medical Sciences, Institute of Medical Sciences, University of Rzeszów, Al. Mjr. W.Kopisto 2a, Rzeszów 35-959, Poland. mdabrowski@ur.edu.pl
Received: April 1, 2024
Revised: August 28, 2024
Accepted: October 29, 2024
Published online: February 15, 2025
Processing time: 272 Days and 23.4 Hours
Core Tip

Core Tip: Adult-onset diabetes is usually considered to be a type 2 diabetes mellitus. However also other types of diabetes, including diabetes in the course of exocrine pancreas diseases, are present at this age. Making an early, correct diagnosis is of utmost importance for the patient's future. Several anthropometric and laboratory parameters were found useful in differentiating these types of diabetes, and on their basis we developed an equation (type 3c diabetes index), which showed the highest sensitivity and specificity in identifying diabetes secondary to pancreatic pathology.