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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Oct 15, 2025; 16(10): 110406
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110406
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110406
Association between Zhejiang University index and metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes mellitus
Xiao-Yan Tao, Tian-Rong Pan, Xing Zhong, Xiao-Yu Pan, Department of Endocrinology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Xiao-Yan Tao, Tian-Rong Pan, Xing Zhong, Xiao-Yu Pan, Research Center for Translational Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China
Author contributions: Pan XY and Tao XY designed the research, performed data curation, formal analysis, and methodology development, managed resources, utilized software, as well as wrote the original draft of the manuscript; Pan TR and Zhong X reviewed and edited the manuscript to ensure its scientific rigor and clarity, contributing critical input in refining the final draft. All authors approved the final version to publish.
Supported by Health Research Program of Anhui, No. AHWJ2023BAc10010; Clinical and Translational Research Project of Anhui Province, No. 202427b10020078.
Institutional review board statement: This study was approved by the Ethics Committee of the Second Affiliated Hospital of Anhui Medical University, No. YX2023-068.
Informed consent statement: Written informed consent for publication was obtained from all patients and/or their families included in this study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The data sets generated and analyzed during this study are not public, but under reasonable requirements, the correspondence author can provide.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Yu Pan, Department of Endocrinology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Economic and Technological Development Zone, Hefei 230601, Anhui Province, China. pxy20201@outlook.com
Received: June 5, 2025
Revised: June 24, 2025
Accepted: September 12, 2025
Published online: October 15, 2025
Processing time: 131 Days and 21.5 Hours
Revised: June 24, 2025
Accepted: September 12, 2025
Published online: October 15, 2025
Processing time: 131 Days and 21.5 Hours
Core Tip
Core Tip: This study is pioneering in its systematic evaluation of the correlation between the Zhejiang University (ZJU) index and metabolic dysfunction-associated steatotic liver disease (MASLD) in patients with type 2 diabetes mellitus (T2DM), and the construction of a new model for predicting MASLD. This study demonstrated that an elevated ZJU index was associated with an increased risk of MASLD in patients with T2DM. The risk of MASLD increased significantly when the ZJU index exceeded 38.87. The novel model developed has been shown to have a satisfactory predictive value for the risk of developing MASLD in patients with T2DM.