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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Oct 15, 2025; 16(10): 110140
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110140
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110140
Analysis of inflammatory response and its factors after dental implant surgery in patients with type 2 diabetes
Zhang-Yi Li, Department of Stomotology, Tianjin Fifth Central Hospital, Tianjin 300070, China
Heng-Yang Yu, Hong Liang, Department of Stomotology, Ecological City Hospital of Tianjin Fifth Central Hospital, Tianjin 300070, China
Author contributions: Li ZY designed the research and wrote the first manuscript; Li ZY, Yu HY and Liang H contributed to conceiving the research and analyzing data; Li ZY conducted the analysis and provided guidance for the research; all authors reviewed and approved the final manuscript.
Supported by Tianjin Municipality Health Science and Technology Project, No. TJWJ2023MS052.
Institutional review board statement: This study was approved by the Ethic Committee of Tianjin Fifth Central Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: There is no conflict of interest.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhang-Yi Li, Department of Stomotology, Tianjin Fifth Central Hospital, No. 41 Zhejiang Road, Tanggu, Binhai New Area, Tianjin 300070, China.
Received: June 5, 2025
Revised: July 9, 2025
Accepted: August 27, 2025
Published online: October 15, 2025
Processing time: 132 Days and 1.4 Hours
Revised: July 9, 2025
Accepted: August 27, 2025
Published online: October 15, 2025
Processing time: 132 Days and 1.4 Hours
Core Tip
Core Tip: Currently, oral rehabilitation is gradually achieved by placing dental implants. Despite generally good success rates for these implants, research shows that patients with diabetes, especially type 2 diabetes mellitus (T2DM), experience more failures. Therefore, the identification of patients at elevated risk for peri-implant inflammatory complications [e.g., peri-implantitis (PI) and peri-implant mucositis] should be prioritized. This study focuses on analyzing the inflammatory response and contributors to postimplant PI in patients with T2DM, providing evidence for reducing the incidence of PI after dental implant surgery.