Review
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2022; 13(3): 150-160
Published online Mar 15, 2022. doi: 10.4239/wjd.v13.i3.150
Efficacy of probiotics on the modulation of gut microbiota in the treatment of diabetic nephropathy
Nozomi Nagase, Yuka Ikeda, Ai Tsuji, Yasuko Kitagishi, Satoru Matsuda
Nozomi Nagase, Yuka Ikeda, Ai Tsuji, Yasuko Kitagishi, Satoru Matsuda, Department of Food Science and Nutrition, Nara Women's University, Nara 630-8506, Japan
Author contributions: Each author has participated sufficiently in the work of drafting the article and/or revising the article for important rational content; all authors give final approval of the version to be submitted.
Conflict-of-interest statement: The authors declare that they have no competing financial interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Satoru Matsuda, MD, PhD, Professor, Department of Food Science and Nutrition, Nara Women's University, Kita-Uoya Nishimachi, Nara 630-8506, Japan. smatsuda@cc.nara-wu.ac.jp
Received: March 5, 2021
Peer-review started: March 5, 2021
First decision: May 3, 2021
Revised: May 21, 2021
Accepted: February 11, 2022
Article in press: February 11, 2022
Published online: March 15, 2022
Processing time: 375 Days and 9.5 Hours
Core Tip

Core tip: Evolving evidence suggests that the gut microbiota may play a key role in the development of diabetic nephropathy (DN). Interventions aimed at the gut microbiota deserve further investigation as a novel protective therapy in DN. We review the potential roles of the gut microbiota in the protection of kidneys and in the development of DN.