Hyperbaric oxygen therapy and chemokine administration - a combination with potential therapeutic value for treating diabetic wounds

doi:10.4239/wjd.v13.i12.1122

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 13, Issue 12

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (5785)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-1) series.

Item

Count

PDF

304

WORD

HTML

2897

Figures (1-1)

626

Tables (1-1)

543

Sum=4426

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

405

Download

951

Sum=1356

Dec 15, 2022 (publication date) through Feb 16, 2026

Times Cited of This Article

Times Cited (6)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Diabetes. Dec 15, 2022; 13(12): 1122-1130
Published online Dec 15, 2022. doi: 10.4239/wjd.v13.i12.1122

Hyperbaric oxygen therapy and chemokine administration - a combination with potential therapeutic value for treating diabetic wounds

Jagannathan Venkataseshan, Pragasam Viswanathan

Jagannathan Venkataseshan, Pragasam Viswanathan, School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014, Tamil Nadu, India

Author contributions: Jaganathan V and Pragasam V designed and wrote the manuscript; and all authors have read and approved the final manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Pragasam Viswanathan, MSc, PhD, Academic Editor, Professor, School of Bio Sciences and Technology, Vellore Institute of Technology, #412B, Renal Research Lab, Pearl Research Park, Vellore 632014, Tamil Nadu, India. pragasam.v@vit.ac.in

Received: August 22, 2022
Peer-review started: August 22, 2022
First decision: September 12, 2022
Revised: September 30, 2022
Accepted: November 4, 2022
Article in press: November 4, 2022
Published online: December 15, 2022
Processing time: 115 Days and 1.6 Hours

Core Tip

Core Tip: Diabetes induces slow or non-healing of wounds, increasing the risk of developing infection and other complications. Proper management of blood sugar levels is essential to improve the overall health. Hyperbaric oxygen therapy (HBOT) enhances the efficacy of wound healing rate in chronic diabetic foot ulcer patients. However, the systemic and meta-analysis data contradicts in cases associated with ischemic wounds. Also, the uncordial functioning of effector cells due to the interrupted signaling pathway involving chemokines and related growth factors worsens the condition of wound healing to a greater extent. Thus, a combinatorial approach of HBOT and chemokine administration could have potential therapeutic value for treating diabetic wounds with the existing clinical protocol.