Kleinaki Z, Agouridis AP, Zafeiri M, Xanthos T, Tsioutis C. Epicardial adipose tissue deposition in patients with diabetes and renal impairment: Analysis of the literature. World J Diabetes 2020; 11(2): 33-41 [PMID: 32064034 DOI: 10.4239/wjd.v11.i2.33]
Corresponding Author of This Article
Constantinos Tsioutis, MD, PhD, Lecturer, School of Medicine, European University Cyprus, 6 Diogenes Street, Nicosia 2404, Cyprus. kostsioutis@gmail.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Feb 15, 2020; 11(2): 33-41 Published online Feb 15, 2020. doi: 10.4239/wjd.v11.i2.33
Epicardial adipose tissue deposition in patients with diabetes and renal impairment: Analysis of the literature
Zoi Kleinaki, Aris P Agouridis, Maria Zafeiri, Theodoros Xanthos, Constantinos Tsioutis
Zoi Kleinaki, Aris P Agouridis, Theodoros Xanthos, Constantinos Tsioutis, School of Medicine, European University Cyprus, Nicosia 2404, Cyprus
Maria Zafeiri, Diabetes and Obesity Center, Konstantopouleio Hospital, Athens 14233, Greece
Author contributions: Kleinaki Z conceptualized and designed the study, participated in data acquisition, extraction and interpretation, prepared tables, wrote and drafted the initial manuscript and approved the final manuscript as submitted; Agouridis AP participated in data analysis and interpretation, reviewed and revised the manuscript and approved the final manuscript as submitted; Zafeiri M conceptualized the study, participated in data interpretation, reviewed and revised the initial manuscript and approved the final manuscript as submitted; Xanthos T participated in data interpretation, reviewed and revised the initial manuscript and approved the final manuscript as submitted; Tsioutis C conceptualized and designed the study, participated in data acquisition, interpreted the data, wrote and drafted the initial manuscript, reviewed and revised the manuscript and approved the final manuscript as submitted.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Constantinos Tsioutis, MD, PhD, Lecturer, School of Medicine, European University Cyprus, 6 Diogenes Street, Nicosia 2404, Cyprus. kostsioutis@gmail.com
Received: September 3, 2019 Peer-review started: August 28, 2018 First decision: October 9, 2018 Revised: December 11, 2019 Accepted: December 14, 2019 Article in press: December 14, 2019 Published online: February 15, 2020 Processing time: 126 Days and 14.9 Hours
Core Tip
Core tip: The epicardial adipose tissue (EAT) is a biologically active organ and has been associated with metabolic diseases and coronary artery disease. EAT is a superior cardiovascular risk factor compared to conventional measures. This editorial evaluates the reported measurements of EAT in patients with diabetes mellitus and renal impairment, along with their clinical and laboratory characteristics. Patients with diabetes mellitus and nephropathy have increased EAT volume, uncontrolled disease, high body mass index and raised cardiovascular risk markers, when compared with healthy population. Based on current literature, EAT assessment could be used as a novel biomarker for the identification of patients at high risk for cardiovascular adverse events.
