Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 15, 2024; 15(6): 1254-1262
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1254
Accuracy of FreeStyle Libre flash glucose monitoring in patients with type 2 diabetes who migrated from highlands to plains
Zeng-Mei Sun, Yuan-Ze Du, Su-Yuan Wang, Shu-Yao Sun, Yan Ye, Xue-Ping Sun, Ming-Xia Li, Hua He, Wun-Chun Long, Cheng-Hui Zhang, Xuan-Yu Yao, Wu-Yi Fan, Ling Wang, Yun-Hong Wu
Zeng-Mei Sun, Yun-Hong Wu, Department of Endocrinology and Metabolism, Hospital of the People's Government of the Tibet Autonomous Region in Chengdu, Chengdu 614000, Sichuan Province, China
Yuan-Ze Du, Department of Nursing, Hospital of Chengdu Office of the People's Government of Tibet Autonomous Region, Chengdu 610041, Sichuan Province, China
Su-Yuan Wang, Shu-Yao Sun, Yan Ye, Xue-Ping Sun, Ming-Xia Li, Hua He, Wun-Chun Long, Cheng-Hui Zhang, Xuan-Yu Yao, Wu-Yi Fan, Ling Wang, Department of Endocrinology, Hospital of Chengdu Office of the People's Government of Tibet Autonomous Region, Chengdu 610041, Sichuan Province, China
Co-first authors: Zeng-Mei Sun and Yuan-Ze Du.
Author contributions: Sun ZM, Wang SY, and Wu YH conceived and designed the study protocol; Sun SY, Li MX, He H, and Zhang CH performed the literature search; Du YZ, Ye Y, Long WC, Fan WY, and Wang L were involved in the data collection; Sun ZM and Du YZ performed the data analysis, and drafted the original manuscript. Sun ZM and Du YZ contributed equally to this work as co-first authors. They are designated as co-first authors as the lead investigators of this work. They took the lead in managing the data collection and data analysis processes and collaborated on the final manuscript and completed revisions. Their contributions were equally significant. Therefore, we believe that designating Sun ZM and Du YZ as co-first authors is fitting for our manuscript. Furthermore, Wu YH, who has a rich academic background, guided the entire process of this work, and is designated as the corresponding author.
Supported by Health and Family Planning Project of Sichuan Province, No. 17PJ069; Tibet Autonomous Region Science and Technology Program, No. XZ202303ZY0011G.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Hospital of Chengdu Office of the People's Government of the TAR, China.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: The datasets generated and analyzed during the study are not publicly available due to the regulations of the hospital. Readers of the article need to discuss with our hospital before the release of the datasets.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun-Hong Wu, Doctor, PhD, Chief Doctor, Chief Physician, Professor, Department of Endocrinology and Metabolism, Hospital of the People's Government of the Tibet Autonomous Region in Chengdu, No. 20 Ximianqiao Hengjie, Wuhou District, Chengdu 614000, Sichuan Province, China. wu_yunhong@163.com
Received: December 15, 2023
Revised: February 2, 2024
Accepted: March 19, 2024
Published online: June 15, 2024
Processing time: 179 Days and 6.3 Hours
ARTICLE HIGHLIGHTS
Research background

Abnormal glucose metabolism in highland populations is an important health concern in our society today.

Research motivation

Identifying highly accurate blood glucose monitoring methods for use in high-altitude populations is an urgent need.

Research objectives

To evaluate the accuracy of the FreeStyle Libre FGM system in highland populations.

Research methods

A total of 66 patients with type 2 diabetes (T2D) were enrolled in this observational analysis. General information and blood glucose data were statistically analyzed.

Research results

The accuracy of the FreeStyle Libre FGM system in patients with T2D who recently migrated from highlands to plains met national and international standards when finger blood glucose levels measured using the enzyme electrode method were used as the standard.

Research conclusions

The FreeStyle Libre FGM system complements continuous glucose monitoring in highland populations.

Research perspectives

Based on the insights gained in this study, we aim to conduct an extended future study on the difference in the mean absolute relative difference values of FGM between patients with normal and elevated hemoglobin and hematocrit levels.