Luo JY, Chen LG, Yan M, Mei YJ, Cui YQ, Jiang M. Effect of individualized nutrition interventions on clinical outcomes of pregnant women with gestational diabetes mellitus. World J Diabetes 2023; 14(10): 1524-1531 [PMID: 37970125 DOI: 10.4239/wjd.v14.i10.1524]
Corresponding Author of This Article
Min Jiang, PhD, Doctor, Clinical Medical College, Yangzhou University, No. 98, Nantong West Road, Yangzhou 225009, Jiangsu Province, China. jiangmin871101@163.com
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Oct 15, 2023; 14(10): 1524-1531 Published online Oct 15, 2023. doi: 10.4239/wjd.v14.i10.1524
Effect of individualized nutrition interventions on clinical outcomes of pregnant women with gestational diabetes mellitus
Jian-Ying Luo, Lang-Gui Chen, Mei Yan, Yue-Jing Mei, Ya-Qian Cui, Min Jiang
Jian-Ying Luo, Department of Clinical Nutrition, Northern Jiangsu People's Hospital of Jiangsu Province, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China
Jian-Ying Luo, Lang-Gui Chen, Yue-Jing Mei, Ya-Qian Cui, Min Jiang, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
Mei Yan, Clinical Medical College, Dalian Medical University, Dalian 116000, Liaoning Province, China
Min Jiang, Department of Gynaecology and Obstetrics, Northern Jiangsu People's Hospital of Jiangsu Province, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China
Author contributions: Luo JY and Chen LG contributed equally to this work; Luo JY and Chen LG designed the research study; Yan M, Mei YJ, Cui YQ and Jiang M contributed reagents and analytic tools; Luo JY, Chen LG and Jiang M analyzed the data; Luo JY and Chen LG wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Northern Jiangsu People's Hospital of Jiangsu Province (Approval No. 2023ky150).
Informed consent statement: This is a retrospective study, and since the analysis used anonymous clinical data approved by the Ethics Committee of Northern Jiangsu People's Hospital of Jiangsu Province, the need for informed consent from subjects or guardians was waived.
Conflict-of-interest statement: The authors declare no competing interests.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Jiang, PhD, Doctor, Clinical Medical College, Yangzhou University, No. 98, Nantong West Road, Yangzhou 225009, Jiangsu Province, China. jiangmin871101@163.com
Received: July 4, 2023 Peer-review started: July 4, 2023 First decision: July 19, 2023 Revised: August 17, 2023 Accepted: September 8, 2023 Article in press: September 8, 2023 Published online: October 15, 2023 Processing time: 97 Days and 1.3 Hours
ARTICLE HIGHLIGHTS
Research background
Gestational diabetes mellitus (GDM) is a kind of impaired glucose tolerance during pregnancy. Women with GDM often have problems such as excessive pregnancy weight gain (PWG), abnormal glucolipid metabolism, and delayed lactation.
Research motivation
Appropriate and effective intervention measures for pregnant women with GDM are of great value and clinical significance to improve maternal and infant outcomes.
Research objectives
This paper intends to determine the effects of individualized nutrition interventions on PWG, glucolipid metabolism, and lactation in pregnant women with GDM.
Research methods
The study population constituted 410 pregnant women with GDM who received treatment at the Northern Jiangsu People's Hospital of Jiangsu Province between December, 2018 and December, 2022, including 200 cases receiving routine interventions [control (Con) group] and 210 cases receiving individualized nutrition interventions [research (Res) group]. PWG, glucolipid metabolism [total cholesterol (TG); triglyceride (TC); fasting blood glucose (FPG); glycosylated hemoglobin (HbA1c)], lactation time, perinatal complications, and neonatal adverse events were collected for comparative analysis.
Research results
A markedly lower PWG and obviously reduced TG, TC, FPG and HbA1c were determined in the Res vs the Con after intervention. In addition, obviously earlier lactation and statistically lower incidences of perinatal complications and neonatal adverse events were determined in the Res.
Research conclusions
Individualized nutrition interventions can reduce PWG in pregnant women with GDM, improve their glucolipid metabolism, and promote early lactation, which deserves clinical promotion.
Research perspectives
This study verified the clinical advantages of individualized nutrition interventions for pregnant women with GDM from the perspectives of PWG, glycolipid metabolism, lactation, perinatal complications, and neonatal adverse events, which can provide a new option for the management of mothers with GDM.
