Xu M, Yang W, Huang T, Zhou J. Diabetic patients with COVID-19 need more attention and better glycemic control. World J Diabetes 2020; 11(12): 644-653 [PMID: 33384770 DOI: 10.4239/wjd.v11.i12.644]
Corresponding Author of This Article
Jun Zhou, MD, Surgeon, Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. doctorzhoujun@163.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Dec 15, 2020; 11(12): 644-653 Published online Dec 15, 2020. doi: 10.4239/wjd.v11.i12.644
Diabetic patients with COVID-19 need more attention and better glycemic control
Ming Xu, Wen Yang, Tao Huang, Jun Zhou
Ming Xu, Wen Yang, Tao Huang, Jun Zhou, Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Author contributions: Zhou J, Huang T, and Xu M designed the study; Yang W collected the data; Xu M analyzed the data; Xu M and Zhou J completed the manuscript; and all authors approved the manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board (IRB) of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors announced no conflict of interest.
Data sharing statement: Please email the corresponding author for the original data.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Zhou, MD, Surgeon, Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. doctorzhoujun@163.com
Received: April 10, 2020 Peer-review started: April 10, 2020 First decision: September 21, 2020 Revised: October 29, 2020 Accepted: November 11, 2020 Article in press: November 11, 2020 Published online: December 15, 2020 Processing time: 246 Days and 14.8 Hours
ARTICLE HIGHLIGHTS
Research background
Coronavirus disease 2019 (COVID-19) is a pandemic disease that results in more than one million deaths. Diabetes is one of the most common comorbidities in COVID-19 patients and possibly increases mortality in patients.
Research motivation
Diabetic patients tend to develop into severe status, leading to poor prognosis. The importance of glycemic control needs to be emphasized.
Research objectives
We attempted to clarify the relationship between diabetes and patients’ severity at the beginning of the pandemic.
Research methods
The clinical characteristics of 61 consecutive patients diagnosed with COVID-19 were collected. The logistic regression was used to calculate ORs of patients’ severity status-related factors.
Research results
Diabetes (OR = 6.29, P = 0.016) and hepatic dysfunction (OR = 5.88, P = 0.018) were independent risk factors for severe disease status in COVID-19 patients in multivariate logistic regression. Poor control of blood glucose (BG) can be seen in diabetic patients.
Research conclusions
In this article, we give evidence on the relationship of diabetes and hepatic dysfunction with patients’ severity in COVID-19 patients. Based on the fact that patients' BG was not well-managed, we appeal to the optimized strategies for diabetes patients with COVID-19.
