Systematic Reviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 15, 2021; 12(8): 1312-1324
Published online Aug 15, 2021. doi: 10.4239/wjd.v12.i8.1312
Which predictors could effect on remission of type 2 diabetes mellitus after the metabolic surgery: A general perspective of current studies?
Gamze Akkus, Tamer Tetiker
Gamze Akkus, Tamer Tetiker, Department of Internal Medicine, Cukurova University Medical Faculty, Adana 33170, Turkey
Gamze Akkus, Tamer Tetiker, Department of Endocrinology, Cukurova University, Adana 33170, Turkey
Author contributions: Akkus A wrote and edited the manuscript; Tetiker T supervised the preparation of the manuscript.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The guidelines of the PRISMA 2009 statement have been adopted.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gamze Akkus, PhD, Academic Research, Department of Endocrinology, Cukurova University Medical Faculty, Sarıcam Street, Adana 33170, Turkey. tugrulgamze@hotmail.com
Received: December 31, 2020
Peer-review started: December 31, 2020
First decision: January 18, 2021
Revised: January 18, 2021
Accepted: April 25, 2021
Article in press: April 25, 2021
Published online: August 15, 2021
Processing time: 221 Days and 3.4 Hours
Abstract
BACKGROUND

The alarming rise in the worldwide prevalence of obesity is paralleled by an increasing burden of type 2 diabetes mellitus (T2DM). Metabolic surgery is the most effective means of obtaining substantial and durable weight loss in individual obese patients with T2DM. There are randomized trials that justify the inclusion of metabolic surgery into the treatment algorithm for patients with T2DM, but remission rates of T2DM after metabolic surgery can display great variability.

AIM

To discuss the most commonly used surgical options including vertical sleeve gastrectomy, adjustable gastric banding, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch.

METHODS

We also report from observational and randomized controlled studies on rate of remission of T2DM after the surgical procedures.

RESULTS

In light of the recent findings, metabolic surgery is a safe and effective treatment option for obese patient with T2DM, but further studies are needed to clarify better the rate of diabetes remission.

CONCLUSION

In light of the recent findings, metabolic surgery is a safe and effective treatment option for obese patients with T2DM, but further studies are needed to clarify better the rate of diabetes remission.

Keywords: Metabolic surgery; Type 2 diabetes mellitus; Vertical sleeve gastrectomy; Biliopancreatic diversion

Core Tip: There are randomized trials that justify the inclusion of metabolic surgery into the treatment algorithm for patients with type 2 diabetes mellitus (T2DM), but remission rates of T2DM after metabolic surgery can display great variability. Here, we discuss the most commonly used surgical options, including vertical sleeve gastrectomy, adjustable gastric banding, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch, and clarify the unknown issues of metabolic surgery and remission criteria of T2DM.