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©2011 Baishideng Publishing Group Co.
World J Gastrointest Oncol. Dec 15, 2011; 3(12): 175-181
Published online Dec 15, 2011. doi: 10.4251/wjgo.v3.i12.175
Published online Dec 15, 2011. doi: 10.4251/wjgo.v3.i12.175
Cancer | Author | Gene | rs number | Location | Study subjects | ||||
Ethnic area | Cases | Controls | Statistical significance | Brief description | |||||
Oral cancer | Hsu[28] | XRCC5 | 828907 | Promoter | Taiwan | 600 | 600 | S | Allele C is of higher risk |
11685387 | Promoter | NS | |||||||
9288518 | Intron 19 | NS | |||||||
Bau[27] | XRCC6 | 5751129 | Promoter | Taiwan | 318 | 318 | S | Allele T is of higher risk, and interacted with betel quid chewing habits | |
2267437 | Promoter | NS | |||||||
132770 | Promoter | NS | |||||||
132774 | Intron 3 | NS | |||||||
Esophageal cancer | Dong[40] | XRCC5 | Accession number: DQ7874341 | Intron16 | China mainland | 329 | 631 | S | Allele A is of higher risk |
Accession number: DQ7874341 | Intron16 | NS | |||||||
Gastric cancer | Dong[40] | XRCC5 | Accession number: DQ7874341 | Intron16 | China mainland | 255 | 631 | S | Allele A is of higher risk |
Accession number: DQ7874341 | Intron16 | S | Allele G is of higher risk | ||||||
Colorectal cancer | Yang[51] | XRCC5 | 828907 | Promoter | Taiwan mainland | 362 | 362 | S | Allele T is of higher risk, and interacted with smoking habits |
11685387 | Promoter | NS | |||||||
9288518 | Intron 19 | NS |
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Citation: Yang MD, Tsai CW, Chang WS, Tsou YA, Wu CN, Bau DT. Predictive role of
XRCC5 /XRCC6 genotypes in digestive system cancers. World J Gastrointest Oncol 2011; 3(12): 175-181 - URL: https://www.wjgnet.com/1948-5204/full/v3/i12/175.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v3.i12.175