Effects of Shenqi Xiangyi granules in advanced gastric cancer chemotherapy

Table 1 Comparison of the recent effects between the two groups, n (%)

Group	CR	PR	SD	PD	Objective mitigation rate
Observation (n = 58)	5 (8.62)	27 (46.55)	23 (39.66)	3 (5.17)	32 (55.17)
Control (n = 58)	1 (1.72)	20 (34.48)	29 (50.00)	8 (13.79)	21 (36.21)
χ2					4.204
P value					0.040

CR: Complete remission; PR: Partial remission; SD: Stable disease; PD: Progression disease.

Table 2 Comparison of immune function indicators between the two groups before treatment (mean ± SD)

Group	CD3+ (%)	CD4+ (%)	CD8+ (%)	CD4+/CD8+	Treg cell (%)	NK cell (%)
Observation (n = 58)	42.86 ± 4.86	26.95 ± 3.10	31.04 ± 2.08	0.87 ± 0.12	5.80 ± 1.04	30.24 ± 4.85
Control (n = 58)	43.10 ± 4.96	27.05 ± 3.18	30.85 ± 2.12	0.88 ± 0.13	5.76 ± 1.08	29.82 ± 4.90
t	0.263	0.171	0.487	0.430	0.203	0.464
P value	0.793	0.864	0.627	0.668	0.839	0.644

Tregs: Regulatory T-cells; NK cell: Natural killer cells.

Table 3 Comparison of immune function indicators between the two groups after treatment (mean ± SD)

Group	CD3+ (%)	CD4+ (%)	CD8+ (%)	CD4+/CD8+	Treg cell (%)	NK cell (%)
Observation (n = 58)	61.28 ± 5.84a	38.84 ± 3.58a	21.58 ± 2.08a	1.81 ± 0.18a	2.08 ± 0.65a	21.26 ± 3.28a
Control (n = 58)	52.84 ± 5.80a	33.10 ± 3.48a	24.63 ± 2.12a	1.34 ± 0.14a	3.07 ± 0.72a	24.95 ± 3.35a
t	7.809	8.756	7.821	15.697	7.773	5.994
P value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

^aP < 0.05.

Tregs: Regulatory T-cells; NK cell: Natural killer cells.

Table 4 Comparison of the two toxic groups, n (%)

Group	White blood cell reduction		Platelet reduction		Liver and kidney function injury
	Level 1-2	Level 3-4	Level 1-2	Level 3-4	Level 1-2	Level 3-4
Observation (n = 58)	22 (37.93)	0	18 (31.03)	0	13 (22.41)	0
Control (n = 58)	31 (53.45)	3 (5.17)	20 (34.48)	2 (3.45)	23 (39.66)	0
χ2	4.971		0.611		4.028
P value	0.026		0.435		0.045

Table 5 Comparison of the two toxic groups, n (%)

Group	Nausea and vomiting		Hand-foot syndrome		Senses the abnormalities in peripheral nerves
	Level 1-2	Level 3-4	Level 1-2	Level 3-4	Level 1-2	Level 3-4
Control (n = 58)	21 (36.21)	1 (1.72)	3 (5.17)	0	6 (10.34)	0
Observation (n = 58)	33 (56.90)	3 (5.17)	5 (8.62)	0	9 (15.52)	0
χ2	6.759		0.134		0.689
P value	0.009		0.714		0.406