Wang R, Zuo CL, Zhang R, Zhu LM. Carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in gastric cancer and their relationship with clinical prognosis. World J Gastrointest Oncol 2023; 15(8): 1475-1485 [PMID: 37663935 DOI: 10.4251/wjgo.v15.i8.1475]
Corresponding Author of This Article
Li-Mei Zhu, MM, Chief Doctor, Department of Medical Laboratory, The First People’s Hospital of Lianyungang, No. 182 Tongguan North Road, Lianyungang 222002, Jiangsu Province, China. zlm5902@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Aug 15, 2023; 15(8): 1475-1485 Published online Aug 15, 2023. doi: 10.4251/wjgo.v15.i8.1475
Table 1 Comparison of general data between the two groups
Group
n
Gender (n)
Age (yr)
Smoking history (case)
Alcohol history (n)
Male
Female
Yes
No
Yes
No
Gastric cancer group
87
46
41
59.11 ± 6.02
52
35
56
31
Control group
80
41
39
58.94 ± 5.76
43
37
45
35
χ2
0.044
0.186
0.616
1.149
P value
0.834
0.853
0.433
0.284
Table 2 Comparison of serum carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 levels between the two groups
Group
n
CEA (ng/mL)
CA199 (U/mL)
CA724 (U/mL)
Gastric cancer group
87
23.69 ± 4.83
52.75 ± 8.52
41.32 ± 6.53
Control group
80
2.58 ± 0.79
4.62 ± 1.49
5.10 ± 1.27
t value
38.611
49.819
48.759
P value
< 0.001
< 0.001
< 0.001
Table 3 Comparison of serum carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 levels in patients with different stages of gastric cancer
Table 4 Comparison of the positive rates of single and combined detection of carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in patients with gastric cancer
Table 5 Comparison of positive rates of single and combined detection of serum carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in patients with different stages of gastric cancer, n (%)
Table 6 Relationship between serum carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 levels and clinicopathology in patients with gastric cancer
Table 7 Comparison of serum carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 levels before and after operation in 87 patients with gastric cancer
Group
n
CEA (ng/mL)
CA199 (U/mL)
CA724 (U/mL)
Before procedure
87
33.11 ± 3.63
57.72 ± 6.64
31.23 ± 3.45
After procedure
87
7.24 ± 1.81
14.23 ± 2.37
4.12 ± 1.12
t value
59.488
57.536
69.712
P value
< 0.001
< 0.001
< 0.001
Citation: Wang R, Zuo CL, Zhang R, Zhu LM. Carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in gastric cancer and their relationship with clinical prognosis. World J Gastrointest Oncol 2023; 15(8): 1475-1485