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©The Author(s) 2020.
World J Gastrointest Oncol. May 15, 2020; 12(5): 592-600
Published online May 15, 2020. doi: 10.4251/wjgo.v12.i5.592
Published online May 15, 2020. doi: 10.4251/wjgo.v12.i5.592
Table 1 General characteristics of rectal cancer patients
| Variable | RC |
| Age (mean ± SD) | 62.27 ± 10.74 |
| Gender (male/female), n (%) | 150 (61)/90 (29) |
| BMI (mean ± SD) | 25.27 ± 3.55 |
| T stage, n (%) | |
| 1 | 42 (17) |
| 2 | 56 (23) |
| 3 | 117 (48) |
| 4 | 30 (12) |
| N stage, n (%) | |
| 0 | 146 (60) |
| 1 | 61 (25) |
| 2 | 38 (15) |
| TNM stage AJCC, n (%) | |
| I | 87 (36) |
| II | 59 (24) |
| III | 99 (40) |
| Patological differentiation, n (%) | |
| Well | 188 (76) |
| Moderate | 50 (21) |
| Poor | 7 (3) |
| Lymphovascular invasion, n (%) | |
| Absent | 153 (62) |
| Present | 92 (38) |
| Perineural invasion, n (%) | |
| Absent | 199 (81) |
| Present | 46 (19) |
| Residual status, n (%) | |
| R0 | 212 (87) |
| R1 | 33 (13) |
| Adjuvant therapy, n (%) | |
| Yes | 104 (42) |
| No | 141 (58) |
| Smoking, n (%) | |
| Ever | 173 (70) |
| Never | 72 (30) |
| Average size of tumor (mm) | 152 ± 292 |
Table 2 Clinicopathological characteristics in patients with and without perineural invasion and lymphovascular invasion
| Characteristics | PNI absent | PNI present | P value | LVI absent | LVI present | P value |
| Age | 62.39 ± 10.58 | 61.72 ± 11.58 | 0.730 | 61.89 ± 10.52 | 62.89 ± 11.14 | 0.491 |
| Gender (male/female) | 123/76 | 27/19 | 0.409 | 97/56 | 53/39 | 0.222 |
| BMI | 25.46 ± 3.58 | 24.40 ± 3.33 | 0.067 | 25.66 ± 3.66 | 25.61 ± 3.27 | 0.270 |
| CEA | 11.58 ± 38.33 | 31.37 ± 148.37 | 0.379 | 9.85 ± 39.11 | 24.44 ± 108.03 | 0.223 |
| CA 19-9 | 16.86 ± 23.88 | 48.24 ± 158.40 | 0.192 | 15.64 ± 22.25 | 34.74 ± 114.60 | 0.123 |
| T stage, n (%) | ||||||
| T1 | 42 (100) | 0 (0) | 0.000 | 41 (98) | 1 (2) | 0.000 |
| T2 | 54 (96) | 2 (4) | 44 (79) | 12 (21) | ||
| T3 | 90 (77) | 27 (23) | 59 (50) | 58 (50) | ||
| T4 | 13 (43) | 17 (57) | 9 (30) | 21 (70) | ||
| N stage, n (%) | ||||||
| 0 | 137 (94) | 9 (6) | 0.000 | 123 (84) | 23 (16) | 0.000 |
| 1 | 39 (64) | 22 (36) | 24 (39) | 37 (61) | ||
| 2 | 23 (60) | 15 (40) | 6 (16) | 32 (84) | ||
| TNM, n (%) | ||||||
| Stage I | 86 (99) | 1 (1) | 0.000 | 81 (93) | 6 (7) | 0.000 |
| Stage II | 51 (86) | 8 (14) | 42 (71) | 17 (29) | ||
| Stage III | 62 (63) | 37 (37) | 30 (30) | 69 (70) | ||
| Differentiation grade, n (%) | ||||||
| Well | 157 (83) | 31 (17) | 0.023 | 125 (66) | 63 (34) | 0.018 |
| Moderate | 39 (78) | 11 (22) | 25 (50) | 25 (50) | ||
| Poor | 3 (43) | 4 (57) | 3 (43) | 4 (57) |
- Citation: Stojkovic Lalosevic M, Milovanovic T, Micev M, Stojkovic M, Dragasevic S, Stulic M, Rankovic I, Dugalic V, Krivokapic Z, Pavlovic Markovic A. Perineural invasion as a prognostic factor in patients with stage I-III rectal cancer – 5-year follow up. World J Gastrointest Oncol 2020; 12(5): 592-600
- URL: https://www.wjgnet.com/1948-5204/full/v12/i5/592.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v12.i5.592