Prognostic significance of baseline C-reactive protein/albumin ratio for long-term outcomes in advanced gastric cancer under immunochemotherapy

doi:10.4251/wjgo.v18.i6.117582

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Jun 15, 2026; 18(6): 117582
Published online Jun 15, 2026. doi: 10.4251/wjgo.v18.i6.117582

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Figure 1 Effects of different C-reactive protein/albumin ratio index on the long-term prognosis of gastric cancer patients. A: Kaplan-Meier plot of progression-free survival in the C-reactive protein/albumin ratio (CAR) index < 0.21 and CAR index ≥ 0.21 groups; B: Kaplan-Meier plot of overall survival in the CAR index < 0.21 and CAR index ≥ 0.21 groups. CAR: C-reactive protein/albumin ratio; PFS: Progression-free survival; OS: Overall survival; CI: Confidence interval.

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Figure 2 Graph depicting the prognostic model for predicting 9-, 12-, and 15-month progression-free survival. PD-L1: Programmed death-ligand 1; CAR: C-reactive protein/albumin ratio; CPS: Combined positive score; MMR: Mismatch repair; pMMR: Proficient mismatch repair; dMMR: Deficient mismatch repair.

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Figure 3 Graph depicting the prognostic model for predicting 12-, 15-, and 18-month overall survival. PD-L1: Programmed death-ligand 1; CAR: C-reactive protein/albumin ratio; CPS: Combined positive score; MMR: Mismatch repair; pMMR: Proficient mismatch repair; dMMR: Deficient mismatch repair.

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Figure 4 Graph illustrating the receiver operating characteristic curves for a prognostic model. A: Receiver operating characteristic (ROC) curves for the training set 9-, 12-, and 15-month progression-free survival (PFS); B: ROC curves for the validation set 9-, 12-, and 15-month PFS; C: ROC curves for the training set 12-, 15-, and 18-month overall survival (OS); D: ROC curves for the validation set 12-, 15-, and 18-month OS. AUC: Area under the curve.

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Figure 5 Graph illustrating the calibration plots for a prognostic model. A: Calibration plots for the training set 9-, 12-, and 15-month progression-free survival (PFS); B: Calibration plots for the validation set 9-, 12-, and 15-month PFS; C: Calibration plots for the training set 12-, 15-, and 18-month overall survival (OS); D: Calibration plots for the validation set 12-, 15-, and 18-month OS.

Citation: Mei S, Ye ML, Hao QL, Li GC, Yao ZY, Wang HY. Prognostic significance of baseline C-reactive protein/albumin ratio for long-term outcomes in advanced gastric cancer under immunochemotherapy. World J Gastrointest Oncol 2026; 18(6): 117582
URL: https://www.wjgnet.com/1948-5204/full/v18/i6/117582.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i6.117582

Mei S, Ye ML, Hao QL, Li GC, Yao ZY, Wang HY. Prognostic significance of baseline C-reactive protein/albumin ratio for long-term outcomes in advanced gastric cancer under immunochemotherapy. World J Gastrointest Oncol 2026; 18(6): 117582 [DOI: 10.4251/wjgo.v18.i6.117582]

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