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©The Author(s) 2020.
World J Gastrointest Oncol. Apr 15, 2020; 12(4): 492-502
Published online Apr 15, 2020. doi: 10.4251/wjgo.v12.i4.492
Published online Apr 15, 2020. doi: 10.4251/wjgo.v12.i4.492
Figure 1 miR-654-5p and miR-376b-3p showed significance differences between tumor specimens and adjacent noncancerous tissues and associated with aggressive progression and poor prognosis of colon cancer.
A: miR-654-5p is up-regulated in colon tumor tissues. The miR-654-5p significantly increased in colon tumor samples compared to in matched noncancerous tissues; B: Kaplan-Meier curves of different miR-654-5p expression levels based on The Cancer Genome Atlas data. The overall survival of patients with colon varies with different miR-654-5p expression levels; C: MiR-376b-3p is downregulated in colon tumor tissues. The miR-376b-3p significantly decreased in colon tumor samples compared to in matched noncancerous tissues; D: Kaplan-Meier curves of different miR-376b-3p expression levels based on The Cancer Genome Atlas data. The overall survival of patients with colon varies with different miR-376b-3p expression levels.
Figure 2 Kaplan-Meier curves of different miR-654-5p expression levels based on The Cancer Genome Atlas data.
A: The overall survival of stage Ipatients with colon varies with different miR-654-5p expression levels; B: The overall survival of stage II patients with colon varies with different miR-654-5p expression levels; C: The overall survival of stage III patients with colon varies with different miR-654-5p expression levels; D: The overall survival of stage IV patients with colon varies with different miR-654-5p expression levels.
Figure 3 Kaplan-Meier curves of different miR-376b-3p expression levels based on The Cancer Genome Atlas data.
A: The overall survival of stage I patients with colon varies with different miR-376b-3p expression levels; B: The overall survival of stage II patients with colon varies with different miR-376b-3p expression levels; C: The overall survival of stage III patients with colon varies with different miR-376b-3p expression levels; D: The overall survival of stage IV patients with colon varies with different miR-376b-3p expression levels.
- Citation: Li P, Cai JX, Han F, Wang J, Zhou JJ, Shen KW, Wang LH. Expression and significance of miR-654-5p and miR-376b-3p in patients with colon cancer. World J Gastrointest Oncol 2020; 12(4): 492-502
- URL: https://www.wjgnet.com/1948-5204/full/v12/i4/492.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v12.i4.492