©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2016; 8(10): 725-734
Published online Oct 15, 2016. doi: 10.4251/wjgo.v8.i10.725
Published online Oct 15, 2016. doi: 10.4251/wjgo.v8.i10.725
Mucins in neoplasms of pancreas, ampulla of Vater and biliary system
Dimitrios Moschovis, Department of Gastroenterology, Agios Panteleimon General Hospital, 18453 Nikea, Greece
Giorgos Bamias, Academic Department of Gastroenterology, Medical School, National and Kapodistrian University of Athens, Laikon Hospital, 11527 Athens, Greece
Ioanna Delladetsima, First Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Correspondence to: Ioanna Delladetsima, Associate Professor, First Department of Pathology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Goudi, 11527 Athens, Greece. jokadelladetsima@hotmail.com
Telephone: +30-210-7456485 Fax: +30-213-2061794
Received: May 10, 2016
Peer-review started: May 11, 2016
First decision: July 4, 2016
Revised: July 19, 2016
Accepted: August 15, 2016
Article in press: August 15, 2016
Published online: October 15, 2016
Processing time: 142 Days and 19 Hours
Peer-review started: May 11, 2016
First decision: July 4, 2016
Revised: July 19, 2016
Accepted: August 15, 2016
Article in press: August 15, 2016
Published online: October 15, 2016
Processing time: 142 Days and 19 Hours
Core Tip
Core tip: The combined status of mucin expression may be useful in the differential diagnosis of pancreatobiliary neoplasms, the detection of pre-malignant lesions and the evaluation of their malignant behavior. Besides their diagnostic and prognostic role, their involvement in carcinogenesis reveals their importance as putative therapeutic targets in the future.