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World J Gastrointest Oncol. Sep 15, 2013; 5(9): 186-194
Published online Sep 15, 2013. doi: 10.4251/wjgo.v5.i9.186
Published online Sep 15, 2013. doi: 10.4251/wjgo.v5.i9.186
Primary hepatocellular carcinoma and metabolic syndrome: An update
Rubayat Rahman, Ghassan M Hammoud, Ashraf A Almashhrawi, Khulood T Ahmed, Jamal A Ibdah, Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65212, United States
Author contributions: Rahman R wrote and revised the manuscript; Hammoud GM, Almashhrawi AA and Ahmed KT were involved in reviewing the literature and collecting data; Ibdah JA conceived the topic, contributed to the writing, analyzed and edited the manuscript, and provided overall intellectual input into the design and execution of the manuscript.
Supported by Raymond E and Vaona H Peck Chair in Cancer Research
Correspondence to: Jamal A Ibdah, MD, PhD, Professor, Director, Division of Gastroenterology and Hepatology, University of Missouri-Columbia, 319 Jesse Hall, Columbia, MO 65212, United States. ibdahj@health.missouri.edu
Telephone: +1-573-8827349 Fax: +1-573-8844595
Received: May 26, 2013
Revised: August 14, 2013
Accepted: August 20, 2013
Published online: September 15, 2013
Processing time: 42 Days and 24 Hours
Revised: August 14, 2013
Accepted: August 20, 2013
Published online: September 15, 2013
Processing time: 42 Days and 24 Hours
Core Tip
Core tip: Hepatocellular carcinoma is a common malignancy with dismal outcome. The metabolic syndrome has been implicated for the recent increase in hepatocellular carcinoma. Numerous studies have shown a strong association between hepatocellular carcinoma and the metabolic syndrome. This review summarizes the current literature linking hepatocellular carcinoma and the metabolic syndrome.