Haverkos BM, Oza VM, Johnson A, Walker J, Shana’ah A. Rare presentation of post-transplant lymphoproliferative disorder isolated to gastroesophageal junction. World J Gastrointest Oncol 2013; 5(12): 230-234 [PMID: 24363831 DOI: 10.4251/wjgo.v5.i12.230]
Corresponding Author of This Article
Veeral M Oza, MD, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, 2nd Floor, Columbus, OH 43210, United States. veeral.oza@osumc.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Dec 15, 2013; 5(12): 230-234 Published online Dec 15, 2013. doi: 10.4251/wjgo.v5.i12.230
Rare presentation of post-transplant lymphoproliferative disorder isolated to gastroesophageal junction
Brad M Haverkos, Veeral M Oza, Andrea Johnson, Jon Walker, Arwa Shana’ah
Brad M Haverkos, Department of Medicine, Division of Hematology and Medical Oncology, Ohio State University, Wexner Medical Center, Columbus, OH 43210, United States
Veeral M Oza, Jon Walker, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Ohio State University, Wexner Medical Center, Columbus, OH 43210, United States
Andrea Johnson, Department of Medicine, Division of Internal Medicine, Ohio State University, Wexner Medical Center, Columbus, OH 43210, United States
Arwa Shana’ah, Department of Pathology, Ohio State University, Wexner Medical Center, Columbus, OH 43210, United States
Author contributions: All authors were involved in management of the patient and writing and editing of this case report; Shana’ah A provided the pathology photographs that are in this article; Oza VM, Walker J, Johnson A and Haverkos BM were involved with admitting, and managing this patient thru the hospitalization.
Correspondence to: Veeral M Oza, MD, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, 2nd Floor, Columbus, OH 43210, United States. veeral.oza@osumc.edu
Telephone: +1-614-2936255 Fax: +1-614-2938518
Received: October 11, 2013 Revised: November 3, 2013 Accepted: November 15, 2013 Published online: December 15, 2013 Processing time: 66 Days and 23.7 Hours
Core Tip
Core tip: Post transplant lymphoproliferative disorder (PTLD) are a heterogeneous group of lymphoid proliferations associated with immunosuppression following solid organ transplantation (SOT) or allogeneic hematopoietic stem cell transplantation (HSCT). PTLD associated with B-cell esophageal lymphoma is a rare diagnosis. Our patient was identified to have isolated PTLD at the gastroesophageal junction, which has not been reported in the modern era of positron emission tomography-computer tomography. Previous reported cases describe esophageal lymphoma associated with symptoms of dysphagia, odynophagia or esophogastroduodenoscopy (EGD) findings that revealed an associated mass or locoregional lymphadenopathy. However, given the variation in presentation in post-transplant and immunocompromised patients, gastrointestinal symptoms should prompt further investigation with an EGD.
