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World J Gastrointest Oncol. Mar 15, 2026; 18(3): 115824
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115824
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115824
Nomograms in the era of personalized oncologic surgery
Bogdan Gafton, Department of Oncology, Regional Institute of Oncology, Iasi 700483, Romania
Bogdan Gafton, Department of Oncology, Grigore T Popa University of Medicine and Phar macy, Iasi 700115, Romania
Ştefan Morărașu, Gabriel-Mihail Dimofte, Department of Surgery, Grigore T Popa University of Medicine and Pharmacy, Iasi 700115, Romania
Ştefan Morărașu, Gabriel-Mihail Dimofte, Department of Surgical Oncology, Regional Institute of Oncology, Iasi 700483, Romania
Author contributions: Gafton B and Morărașu Ş prepared the design and wrote the manuscript; Dimofte GM supervised the work and critically reviewed the final version of the manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest related to the manuscript.
Corresponding author: Ştefan Morărașu, PhD, MRCP, Department of Surgery, Grigore T Popa University of Medicine and Pharmacy, Universitatii St No 16, Iasi 700115, Romania. morarasu.stefan@gmail.com
Received: October 27, 2025
Revised: November 25, 2025
Accepted: December 31, 2025
Published online: March 15, 2026
Processing time: 136 Days and 19.1 Hours
Revised: November 25, 2025
Accepted: December 31, 2025
Published online: March 15, 2026
Processing time: 136 Days and 19.1 Hours
Core Tip
Core Tip: Personalized oncology increasingly depends on integrating quantitative tools into clinical decision-making. The study by Xie et al introduces a nomogram that combines tumor- and host-related factors (including γ-glutamyl transferase, chloride, activated partial thromboplastic time, N stage, and vascular invasion) to predict survival after colorectal liver metastasis resection. Unlike traditional scores such as Fong or Nordlinger models, this LASSO-Cox–based approach reflects biologic and systemic determinants of outcome. Accessibility and interpretability make it promising for daily surgical oncology practice, emphasizing the ongoing shift toward precision-guided, individualized care in metastatic colorectal cancer.
