Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Oncol. Dec 15, 2026; 18(12): 126212
Published online Dec 15, 2026. doi: 10.4251/wjgo.126212
Published online Dec 15, 2026. doi: 10.4251/wjgo.126212
Liposomal bupivacaine vs ropivacaine for ultrasound-guided transversus abdominis plane block after laparoscopic radical colectomy: Propensity score-matched retrospective study
Yuan-Yuan Gao, Jian Li, Yong-Heng Hou, Ming-Zhu Xu, Hong Ye, Rui Ma, Peng Li, Department of Anesthesiology, The Fourth Affiliated Hospital of Suzhou University, Suzhou 215000, Jiangsu Province, China
Author contributions: Gao YY and Li J conceived and designed the study and served as guarantors; Gao YY performed data curation and formal analysis and drafted the initial manuscript; Hou YH, Xu MZ, Ye H, and Ma R contributed to data acquisition, investigation, and drafting of the initial manuscript; Li J, Hou YH, and Li P critically revised the manuscript for important intellectual content; and all authors reviewed and approved the final version of the manuscript and agree to be accountable for all aspects of the work.
AI contribution statement: The authors declare that no generative artificial intelligence tools were used in the development or writing of this manuscript. The authors retain full responsibility for the integrity, accuracy, and originality of the content.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Fourth Affiliated Hospital of Suzhou University, approval No. 2026 Lunyan 260184.
Informed consent statement: The subjects have signed the informed consent form.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Peng Li, MD, Department of Anesthesiology, The Fourth Affiliated Hospital of Suzhou University, No. 9 Chongwen Road, Suzhou Industrial Park, Suzhou 215000, Jiangsu Province, China. ageline96429@163.com
Received: July 28, 2026
Revised: August 19, 2026
Accepted: October 21, 2026
Published online: December 15, 2026
Processing time: 105 Days and 1.4 Hours
Revised: August 19, 2026
Accepted: October 21, 2026
Published online: December 15, 2026
Processing time: 105 Days and 1.4 Hours
Core Tip
Core Tip: This retrospective propensity score-matched cohort study compared liposomal bupivacaine with ropivacaine for transversus abdominis plane block in patients undergoing laparoscopic radical colectomy. Liposomal bupivacaine was associated with lower pain scores, reduced rescue analgesia and patient-controlled analgesia demands, and faster anesthetic emergence over 48 hours. It was also associated with attenuated postoperative immune suppression and inflammatory activation, without significant differences in delirium or adverse events. However, the two regimens were not dose-equi