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World J Gastrointest Oncol. Dec 15, 2026; 18(12): 124015
Published online Dec 15, 2026. doi: 10.4251/wjgo.124015
Published online Dec 15, 2026. doi: 10.4251/wjgo.124015
Application of perioperative care based on a quantitative evaluation strategy in pancreatic cancer patients undergoing pancreaticoduodenectomy
Zhong-Ling Zheng, Tuan Li, En-Yan Hu, Jia Xue, Lin Ji, Department of Anesthesiology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210000, Jiangsu Province, China
Co-first authors: Zhong-Ling Zheng and Tuan Li.
Author contributions: Zheng ZL and Li T conceived and designed the study and they contribute equally to this study as co-first author; Hu EY collected and verified the clinical data; Xue J performed the statistical analysis; Ji L drafted and critically revised the manuscript; and all authors reviewed and approved the final manuscript.
AI contribution statement: No AI tool was involved in the generation of research data, interpretation of results, or formulation of conclusions. We only translated and polished the response to the reviewers.
Institutional review board statement: This study was approved by the Ethics Committee of Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University.
Informed consent statement: Written informed consent was obtained from all participants or their legal representatives prior to enrollment in the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The data which support the result of this study can be obtained from the corresponding author when reasonable request is made.
Corresponding author: Lin Ji, MB, Department of Anesthesiology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 305 Zhongshan East Road, Xuanwu District, Nanjing 210000, Jiangsu Province, China. m15996277421@163.com
Received: June 5, 2026
Revised: July 10, 2026
Accepted: September 17, 2026
Published online: December 15, 2026
Processing time: 157 Days and 1.1 Hours
Revised: July 10, 2026
Accepted: September 17, 2026
Published online: December 15, 2026
Processing time: 157 Days and 1.1 Hours
Core Tip
Core Tip: This retrospective cohort study examined a locally developed quantitative risk-stratified perioperative care pathway in 260 patients undergoing pancreaticoduodenectomy. Compared with routine care, use of the pathway was associated with less intraoperative blood loss, earlier first flatus, a shorter postoperative hospital stays, fewer recorded complications, and lower anxiety and depression scores at postoperative week 1. These findings support further prospective evaluation of the pathway but do not establish an independent causal effect.