BPG is committed to discovery and dissemination of knowledge
Home / Archive / Volume 18, Issue 11
  • This Article
Peer-Review Report of This Article
CrossCheck and Google Search of This Article
Academic Rules and Norms of This Article
Supplementary Materials of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Oncology
ISSN
1948-5204
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study
Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Oncol. Nov 15, 2026; 18(11): 122505
Published online Nov 15, 2026. doi: 10.4251/wjgo.122505
Exploring the role of the systemic immune-inflammation index in colorectal cancer: A study on screening and prognostic assessment
Juan Xu, Shao-Xue Li
Juan Xu, Shao-Xue Li, Department of Gastroenterology, The Third People’s Hospital of Hefei, The Third Clinical Medical College of Hefei of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Xu J and Li SX designed the research study and drafted and revised the manuscript; Xu J collected the data and performed the research; Li SX analyzed the data; and all authors reviewed the final version and approved the submission.
AI contribution statement: The authors declare that no generative AI or AI-assisted technologies were used in the writing, editing, analysis, or preparation of this manuscript.
Institutional review board statement: The study was approved by the Medical Ethics Committee of the Third People’s Hospital of Hefei (Approval No. 2025 LLWL029).
Informed consent statement: Informed consent for participation in this study was obtained from all patients or their legal representatives.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: The data utilized to substantiate the findings of this study are available upon request from the corresponding authors.
Corresponding author: Juan Xu, Department of Gastroenterology, The Third People’s Hospital of Hefei, The Third Clinical Medical College of Hefei of Anhui Medical University, No. 204 Wangjiang East Road, Hefei 230022, Anhui Province, China. xujuanhfc@163.com
Received: April 21, 2026
Revised: July 24, 2026
Accepted: September 18, 2026
Published online: November 15, 2026
Processing time: 189 Days and 8.3 Hours
Core Tip

Core Tip: This retrospective study explored the clinical value of systemic immune-inflammation index (SII) screening and assessing colorectal adenoma and colorectal cancer (CRC). Receiver operating characteristic curve determined SII’s diagnostic threshold for CRC and precancerous lesions as 480.326. Elevated SII was identified as an independent risk factor for CRC, but preoperative SII has no significant correlation with CRC patients’ overall survival.
Write to the Help Desk
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.