©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2025; 17(3): 102077
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.102077
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.102077
Traditional Chinese medicine and modern technology: Network pharmacology and omics sequencing in gastric cancer
Jessica Shapiro Gemmell, College of Medicine, University of Florida, Gainesville, FL 32601, United States
Brandon Lucke-Wold, Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville, FL 32608, United States
Author contributions: Gemmell JS and Lucke-Wold B wrote the paper; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Corresponding author: Jessica Shapiro Gemmell, College of Medicine, University of Florida, 1104 Newell Dr. Gainesville, FL 32601, United States. jessicashapiro@ufl.edu
Received: October 7, 2024
Revised: December 10, 2024
Accepted: January 2, 2025
Published online: March 15, 2025
Processing time: 129 Days and 11.3 Hours
Revised: December 10, 2024
Accepted: January 2, 2025
Published online: March 15, 2025
Processing time: 129 Days and 11.3 Hours
Core Tip
Core Tip: Gastric cancer (GC) is a heterogenous disease that incorporates the use of multiple metabolic pathways to contribute to tumorigenesis. Modern technology, which includes omics sequencing, has allowed for better characterization of these pathways and more targeted drug development by using natural components in food, nutraceuticals, to enhance treatment. However, current classification of GC as well as treatment does not address the complex nature of this disease. Omics technologies must be applied to characterize the subtypes of GC, which may lead to better application of nutraceu