Huang SF, Yang F, Chen WJ, Zhang XH. Ultrasound features of primary intestinal lymphoma in children and their correlation with prognosis: A two-center experiment. World J Gastrointest Oncol 2025; 17(10): 109450 [PMID: 41114090 DOI: 10.4251/wjgo.v17.i10.109450]
Corresponding Author of This Article
Xue-Hua Zhang, MD, Doctor, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, No. 18 Daoshan Road, Fuzhou 350000, Fujian Province, China. zhangxuehua@fjsetyy.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Oct 15, 2025 (publication date) through Oct 26, 2025
Times Cited of This Article
Times Cited (0)
Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Oncology
ISSN
1948-5204
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Huang SF, Yang F, Chen WJ, Zhang XH. Ultrasound features of primary intestinal lymphoma in children and their correlation with prognosis: A two-center experiment. World J Gastrointest Oncol 2025; 17(10): 109450 [PMID: 41114090 DOI: 10.4251/wjgo.v17.i10.109450]
Sai-Feng Huang, Department of Ultrasound, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou 350011, Fujian Province, China
Fang Yang, Wen-Juan Chen, Department of Ultrasound, The Affiliated Children's Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha 410007, Hunan Province, China
Xue-Hua Zhang, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou 350000, Fujian Province, China
Xue-Hua Zhang, Department of Ultrasound, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), Fuzhou 350011, Fujian Province, China
Co-first authors: Sai-Feng Huang and Fang Yang.
Author contributions: Huang SF, Yang F, Chen WJ, Zhang XH made significant contributions to the writing and editing process; All authors read and approved the final manuscript.
Supported by the Fujian Province Science and Technology Innovation Joint Fund Project, No. 2021Y9188.
Institutional review board statement: The study received approval from the Medical Ethics Committee of Fujian Children’s Hospital (No. 2024ETKLRK10004).
Informed consent statement: This study was a retrospective one and the data was anonymized. The ethics committee agreed to waive the application for signing the informed consent form.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at [E-mail address or URL]. Participants gave informed consent for data sharing was not obtained but the presented data are anonymized and risk of identification is low and the potential benefits of sharing these data outweigh the potential harms because it can enable more doctors to have a deeper understanding of such diseases, better evaluate the treatment plans for children patients, and prolong the quality of life and life cycle of children patients.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Hua Zhang, MD, Doctor, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, No. 18 Daoshan Road, Fuzhou 350000, Fujian Province, China. zhangxuehua@fjsetyy.com
Received: May 12, 2025 Revised: June 21, 2025 Accepted: August 25, 2025 Published online: October 15, 2025 Processing time: 156 Days and 1.8 Hours
Core Tip
Core Tip: In the present retrospective study, our objective was to ascertain the relationship between ultrasonic classification of intestinal lymphoma, lactate dehydrogenase (LDH) levels, pathological classification, and patient prognosis. The findings revealed a significant correlation between ultrasonic classification and LDH levels with patient prognosis. The prognosis for pediatric patients diagnosed with extensive intestinal lymphoma was observed to be less favorable compared to those with localized segmental intestinal lymphoma. From these outcomes, it can be inferred that ultrasonography serves as a valuable tool for the diagnosis and classification of intestinal lymphoma in pediatric patients. Furthermore, the presence of extensive intestinal lymphoma is correlated with markedly elevated LDH which are in of a favorable prognosis.
