Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2025; 17(1): 101581
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.101581
Network pharmacology: Changes the treatment mode of "one disease-one target" in cancer treatment
Shuai Liu, Yong-Wei Yu
Shuai Liu, Department of Cardiology, The First People’s Hospital of Jiashan, Jiaxing 314100, Zhejiang Province, China
Yong-Wei Yu, Department of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Author contributions: Liu S wrote the manuscript; Yu YW designed the study and revised the manuscript; All listed authors consent to the submission.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Wei Yu, PhD, Doctor, Department of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310000, Zhejiang Province, China. yuyongwei@zju.edu.cn
Received: September 19, 2024
Revised: October 7, 2024
Accepted: October 31, 2024
Published online: January 15, 2025
Processing time: 83 Days and 19.5 Hours
Core Tip

Core Tip: Cancer cannot be effectively treated against a single gene target because it involves the synergy of different gene groups. Network pharmacology provides strong evidence of "multicomponent-multitarget" synergistic effects for the treatment of cancer with Chinese medicine.