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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Curcumin for gastric cancer: Mechanism prediction via network pharmacology, docking, and in vitro experiments
Peng-Hui Yang, Ya-Nan Wei, Bi-Juan Xiao, Si-Yi Li, Xin-Long Li, Liang-Jun Yang, Hua-Feng Pan, Geng-Xin Chen
Peng-Hui Yang, Ya-Nan Wei, The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China
Bi-Juan Xiao, Xin-Long Li, Hua-Feng Pan, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China
Si-Yi Li, Department of Traditional Chinese Medicine, The People's Hospital of Longhua, Shenzhen 518109, Guangdong Province, China
Liang-Jun Yang, Department of Gastroenterology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Geng-Xin Chen, Centre for Translational Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Author contributions: All authors contributed to the conceptualization and composition of this manuscript; Yang PH, Wei YN and Xiao BJ wrote the paper; Li SY, Li XL and Yang LJ assisted in data collection and analysis; Chen GX and Pan HF contributed to the study design; Chen GX made critical revisions to this paper; All authors have reviewed and approved the final version of the manuscript.
Supported by the National Nature Science Foundation of China, No. 81273735 and No. 82174319; the Natural Science Foundation of Guangdong Province, China, No. 2021A1515010961; the Key-Area Research and Development Program of Guangdong Province, China, No. 2020B1111100011; and the China Postdoctoral Science Foundation, China, No. 2023M740859.
Institutional animal care and use committee statement: The study did not involve any human or animal experiments, and the data is derived from cells or tissues experiments and databases. BGC-823 cell line used in the study was purchased from Guangzhou Jennio Biotech Co., Ltd, China.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest regarding the publication of this paper. The authors affirm that this research is conducted in an unbiased manner and that the findings and conclusions presented are solely based on scientific merit.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Geng-Xin Chen, MD, Chief Doctor, Centre for Translational Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 111 Dade Road, Guangzhou 510120, Guangdong Province, China.
gxchen@gzucm.edu.cn
Received: April 15, 2024
Revised: May 24, 2024
Accepted: June 18, 2024
Published online: August 15, 2024
Processing time: 115 Days and 1.3 Hours
