Zhang X, Wang Y, Zhu T, Ge J, Yuan JH. Characteristics and risk factor analyses of high-grade intraepithelial neoplasia in older patients with colorectal polyps. World J Gastrointest Oncol 2024; 16(10): 4129-4137 [PMID: 39473943 DOI: 10.4251/wjgo.v16.i10.4129]
Corresponding Author of This Article
Jun-Hua Yuan, Doctor, Professor, Department of Geriatric Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Huaiyin District, Jinan 250021, Shandong Province, China. yjh717299@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xin Zhang, Ying Wang, Tong Zhu, Jun-Hua Yuan, Department of Geriatric Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Jian Ge, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Author contributions: Zhang X and Wang Y were the guarantor and designed the study; Zhang X, Zhu T, and Yuan JH participated in the acquisition, analysis, and interpretation of the data, and drafted the initial manuscript; Zhang X, Ge J and Yuan JH revised the article critically for important intellectual content.
Institutional review board statement: The study was reviewed and approved by the Science and Research Office of Shandong First Medical University Affiliated Provincial Hospital (approved number SWYX: No. 2024-294).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jun-Hua Yuan, Doctor, Professor, Department of Geriatric Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Huaiyin District, Jinan 250021, Shandong Province, China. yjh717299@126.com
Received: July 24, 2024 Revised: August 13, 2024 Accepted: September 5, 2024 Published online: October 15, 2024 Processing time: 63 Days and 22.2 Hours
Core Tip
Core Tip: Elderly patients diagnosed with colorectal polyps admitted to our hospital from January 2021 to December 2023 were included in the study. High-grade intraepithelial neoplasia characteristics and risk factors of elderly colorectal polyps were analyzed, to provide references for early screening, monitoring and treatment of colorectal polyps in the elderly. Studies have found that the occurrence of high-grade neoplasia in colorectal polyps is closely related to its location, size, villous characteristics, family history, and increased level of tumor markers. Based on these factors, it was found that the early diagnosis and treatment of patients with colorectal polyps could be made, which is of great significance to prevent high-grade neoplasia and even further malignant transformation of polyps in these patients.
