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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Sep 15, 2022; 14(9): 1785-1797
Published online Sep 15, 2022. doi: 10.4251/wjgo.v14.i9.1785
Published online Sep 15, 2022. doi: 10.4251/wjgo.v14.i9.1785
Efficacy and safety of laparoscopic radical resection following neoadjuvant therapy for pancreatic ductal adenocarcinoma: A retrospective study
Yong-Gang He, Xiao-Bing Huang, Yu-Ming Li, Jing Li, Xue-Hui Peng, Wen Huang, Yi-Chen Tang, Lu Zheng, Department of Hepatobiliary, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, China
Author contributions: He YG and Huang XB, Zheng L contributed to the conception and design of the study and drafted the manuscript; Zheng L, Li YM, Peng XH, Li J, Huang W and Tang YC contributed to the analysis and interpretation of the data and revised the manuscript; Zheng L, Li YM, and He YG participated in the clinical treatment operation and literature research; and all authors read and approved the final manuscript.
Supported by Chongqing Municipal Science and Technology Talent Project , No. csct2017jcyj-yszxX0002 ; Chongqing Municipal Science and Technology Innovation Project for Social Undertakings and People’s Livelihood Guarantee , No. cstc2018jscx-mszdX0012 ; and the Natural Science Foundation of Chongqing , No. cstc2021jcyj-msxmX0991 .
Institutional review board statement: This retrospective observational study was approved by the Medical Ethics Committee of our hospital and was conducted in accordance with the Declaration of Helsinki and the International Ethical Guidelines for Biomedical Research Involving Human Subjects (2022-r177-01).
Informed consent statement: Written informed consent was obtained from all the patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The authors declare that all the data have been provided in the article and that there are no supplemental data.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lu Zheng, Doctor, MD, PhD, Academic Editor, Chief Doctor, Deputy Director, Director, Doctor, Surgeon, Surgical Oncologist, Department of Hepatobiliary, The Second Affiliated Hospital of Army Medical University, No. 183 Xinqiao High Street, Shapingba District, Chongqing 400037, China. xqyyzl1@163.com
Received: May 23, 2022
Peer-review started: May 23, 2022
First decision: July 6, 2022
Revised: July 16, 2022
Accepted: August 15, 2022
Article in press: August 15, 2022
Published online: September 15, 2022
Processing time: 109 Days and 1.4 Hours
Peer-review started: May 23, 2022
First decision: July 6, 2022
Revised: July 16, 2022
Accepted: August 15, 2022
Article in press: August 15, 2022
Published online: September 15, 2022
Processing time: 109 Days and 1.4 Hours
Core Tip
Core Tip: We retrospectively analyzed the clinical data of 15 patients with pathologically confirmed pancreatic cancer who received neoadjuvant therapy followed by laparoscopic radical surgery in our hospital from December 2019 to April 2022. All patients underwent abdominal contrast-enhanced computed tomography (CT) and positron emission tomography-CT before surgery to accurately assess tumor stages and exclude distant metastasis. This retrospective study demonstrated that laparoscopic radical resection of pancreatic cancer after neoadjuvant therapy is safe and effective if it is performed by a surgeon with rich experience in laparoscopic pancreaticoduodenectomy in a large center of pancreatic surgery.