Effect of exercise on colorectal cancer prevention and treatment

doi:10.4251/wjgo.v11.i5.348

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May 15, 2019 (publication date) through Mar 2, 2026

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. May 15, 2019; 11(5): 348-366
Published online May 15, 2019. doi: 10.4251/wjgo.v11.i5.348

Effect of exercise on colorectal cancer prevention and treatment

Zeynep Oruç, Muhammed Ali Kaplan

Zeynep Oruç, Department of Medical Oncology, Mersin City Hospital, Mersin 33000, Turkey

Muhammed Ali Kaplan, Department of Medical Oncology, Faculty of Medicine, Dicle University, Diyarbakır 21280, Turkey

Author contributions: Oruç Z contributed to writing of the article and investigation of data; Kaplan MA contributed to writing of the article, interpretation, and reviewing.

Conflict-of-interest statement: The authors declare no conflicts of interest.

Corresponding author: Muhammet Ali Kaplan, MD, Associate Professor, Department of Medical Oncology, Faculty of Medicine, Dicle University, Diyarbakır 21280, Turkey. drmalikaplan@hotmail.com

Telephone: +90-53-37677131 Fax: +90-41-22488001

Received: February 25, 2019
Peer-review started: February 26, 2019
First decision: March 15, 2019
Revised: April 15, 2019
Accepted: May 3, 2019
Article in press: May 3, 2019
Published online: May 15, 2019
Processing time: 79 Days and 15.4 Hours

Core Tip

Core tip: This review aimed to investigate the effects of physical activity and the biological basis of these effects in preventing the risk and recurrence of colorectal cancer (CRC) and decreasing the hazards of cancer and cancer treatment. Several observational studies have demonstrated the efficacy and dose-dependent and anti-cancer effects of exercise on decreasing the mortality and risk of recurrence before and after the CRC diagnosis. However, the required exercise dose, type and intensity are yet unclear. The results of randomised prospective studies are expected.