©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2019; 11(10): 768-772
Published online Oct 15, 2019. doi: 10.4251/wjgo.v11.i10.768
Published online Oct 15, 2019. doi: 10.4251/wjgo.v11.i10.768
Cancer-specific metabolism: Promising approaches for colorectal cancer treatment
Keun-Yeong Jeong, The Research Center, Metimedi Pharmaceuticals, Incheon 22006, South Korea
Author contributions: Jeong KY conceived the study and drafted the manuscript; This author approved the final version of the article.
Conflict-of-interest statement: This author has no conflicts of interest to declare.
Corresponding author: Keun-Yeong Jeong, PhD, Executive Vice President, The Research Center, Metimedi Pharmaceuticals, 263, Central-ro, Yeonsu-Gu, Incheon 22006, South Korea. alvirus@naver.com
Telephone: +82-32-2050541 Fax: +82-32-2050542
Received: July 17, 2019
Peer-review started: July 17, 2019
First decision: August 23, 2019
Revised: September 4, 2019
Accepted: September 10, 2019
Article in press: September 10, 2019
Published online: October 15, 2019
Processing time: 105 Days and 6.1 Hours
Peer-review started: July 17, 2019
First decision: August 23, 2019
Revised: September 4, 2019
Accepted: September 10, 2019
Article in press: September 10, 2019
Published online: October 15, 2019
Processing time: 105 Days and 6.1 Hours
Core Tip
Core tip: Studies of cancer-specific metabolism have been conducted for over half a century, and the importance of promoting aerobic glycolysis, cancer favorable metabolic changes in mitochondria, and abnormal expression of drug-metabolizing enzymes has been emphasized through the established theories to date. Cancer-specific metabolism is a major theoretical background that can explain the process of survival and proliferation of most solid cancers. Developing cancer-specific metabolism-target drugs provide a novel treatable method that will be critical in this new area of treatment strategies for colorectal cancer. They have not yet been conquered and have infinite growth potential.