TRIPLET combined with microwave ablation: A novel treatment for advanced hepatocellular carcinoma

doi:10.4251/wjgo.v17.i1.98572

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Jan 15, 2025 (publication date) through Dec 24, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2025; 17(1): 98572
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.98572

TRIPLET combined with microwave ablation: A novel treatment for advanced hepatocellular carcinoma

Fei-Yu Zhao, Guo-Wei Si, Nian-Song Qian

Fei-Yu Zhao, Department of Thoracic Oncology, Respiratory and Critical Care Medicine, The Eighth Medical Center of People’s Liberation Army General Hospital, Beijing 100853, China

Guo-Wei Si, Department of Gastroenterology, Fourth Medical Centre, General Hospital of the People's Liberation Army, Beijing 100142, China

Nian-Song Qian, Senior Department of Thoracic Oncology, Respiratory and Critical Care Medicine, The Eighth Medical Center of People’s Liberation Army General Hospital, Beijing 100091, China

Author contributions: Zhao FY wrote this paper; Si GW revised it; Qian NS provided ideas for writing it.

Conflict-of-interest statement: There are no conflicts of interest in this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Nian-Song Qian, MD, Chief Physician, Senior Department of Thoracic Oncology, Respiratory and Critical Care Medicine, The Eighth Medical Center of People’s Liberation Army General Hospital, No. 28 Fuxing Road, Beijing 100091, China. qianniansong1@163.com

Received: June 29, 2024
Revised: August 21, 2024
Accepted: September 9, 2024
Published online: January 15, 2025
Processing time: 165 Days and 18.2 Hours

Abstract

This editorial comments on a study by Zuo et al. The focus is on the efficacy of hepatic arterial infusion chemotherapy combined with camrelizumab and apatinib (the TRIPLET regimen), alongside microwave ablation therapy, in treating advanced hepatocellular carcinoma (HCC). The potential application of this combination therapy for patients with advanced HCC is evaluated.

Keywords: Microwave ablation; Hepatic arterial infusion chemotherapy; Apatinib; Camrelizumab; Hepatocellular carcinoma

Core Tip: This article examines the efficacy of combining microwave ablation with the TRIPLET regimen in patients with advanced hepatocellular carcinoma. While both treatments show promise individually, their combined efficacy and safety require further clinical investigation.