Yan ZW, Liu YN, Xu Q, Yuan Y. Current trends and hotspots of depressive disorders with colorectal cancer: A bibliometric and visual study. World J Gastrointest Oncol 2024; 16(8): 3687-3704 [PMID: 39171183 DOI: 10.4251/wjgo.v16.i8.3687]
Corresponding Author of This Article
Yuan Yuan, MD, PhD, Professor, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, No. 155 NanjingBei Street, Heping District, Shenyang 110001, Liaoning Province, China. yuanyuan@cmu.edu.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Scientometrics
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3687-3704 Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3687
Current trends and hotspots of depressive disorders with colorectal cancer: A bibliometric and visual study
Zi-Wei Yan, Ying-Nan Liu, Qian Xu, Yuan Yuan
Zi-Wei Yan, Ying-Nan Liu, Qian Xu, Yuan Yuan, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Zi-Wei Yan, Ying-Nan Liu, Qian Xu, Yuan Yuan, Key Laboratory of Cancer Etiology and Prevention in Liaoning Education Department, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Zi-Wei Yan, Ying-Nan Liu, Qian Xu, Yuan Yuan, Key Laboratory of GI Cancer Etiology and Prevention in Liaoning Province, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Co-first authors: Zi-Wei Yan and Ying-Nan Liu.
Author contributions: Yuan Y conceived and revised the full text; Yan ZW systematically collected literature and drafted the manuscript; Liu YN processed some of the data and proofread the manuscript; Xu Q was partially involved in the study design; All authors have read and approved the final manuscript. Yan ZW and Liu YN contributed equally to this work as co-first authors.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yuan Yuan, MD, PhD, Professor, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, No. 155 NanjingBei Street, Heping District, Shenyang 110001, Liaoning Province, China. yuanyuan@cmu.edu.cn
Received: January 11, 2024 Revised: May 26, 2024 Accepted: June 17, 2024 Published online: August 15, 2024 Processing time: 209 Days and 13.8 Hours
Abstract
BACKGROUND
Depression is strongly associated with colorectal cancer (CRC). Few bibliometric analyses have systematically summarized the research focus and recent progress in this field.
AIM
To determine the research status and hotspots by bibliometric analysis of relevant publications on the relationship between CRC and depression.
METHODS
Articles on depression in CRC patients were collected from the Web of Science Core Collection. CiteSpace and VOSviewer software were used to visualize bibliometric networks.
RESULTS
From 2001 to 2022, Supportive Care in Cancer, the United States, Tilburg University, and Mols were the most productive and influential journal, country, institution, and author name. Co-occurrence cluster analysis of keywords placed quality of life, anxiety, and psychological stress in the center of the visual network diagram. Further clustering was performed for the clusters with studies of the relevant mechanism of action, which showed that: (1) Cytokines have a role essential for the occurrence and development of depressive disorders in CRC; (2) MicroRNAs have a role essential for the development of depressive disorders in CRC; (3) Some anticancer drugs have pro-depressant activity; and (4) Selective serotonin reuptake inhibitors have both antitumor and antidepressant activity.
CONCLUSION
Life quality and psychological nursing of the cancer population were key topics. The roles of cytokines and microRNAs, the pro-depression activity of anticancer drugs and their antitumor properties deserve in-depth study.
Core Tip: Colorectal cancer (CRC) is the third leading cause of cancer-related death. The impact of psychological disorders on the treatment of CRC is significant, Patients with severe psychological disorders experience reduced quality of life, poor treatment compliance, prolonged recovery time, abnormal disease behavior, damage to social relationships, and poor survival. There is no systematic summary and comparison of the status and trend of research on the impact of depression on CRC. Bibliometric analysis is known as a method of rigorous, quantitative analysis of a large volume of data contained in the scientific literature. It is necessary to investigate the relationship between CRC and depression.
