Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3368-3371
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3368
Remazolam combined with transversus abdominis plane block in gastrointestinal tumor surgery: Have we achieved better anesthetic effects?
Jing Cao, Xing-Liao Luo, Qiang Lin
Jing Cao, Xing-Liao Luo, Department of Anesthesiology, North China Petroleum Bureau General Hospital, Renqiu 062552, Hebei Province, China
Qiang Lin, Department of Oncology, North China Petroleum Bureau General Hospital, Hebei Medical University, Renqiu 062552, Hebei Province, China
Author contributions: Cao J completed manuscript preparation; Luo XL provided assistance for manuscript preparation; Lin Q provided comprehensive guidance and constructive feedback on the manuscript. All authors have read the final manuscript.
Supported by Health Commission of Hebei Province, China, No. 20240074; and Scientific Research Project of Hebei Provincial Administration of Traditional Chinese Medicine, China, No. 2024317.
Conflict-of-interest statement: All authors have nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiang Lin, MD, PhD, Professor, Department of Oncology, North China Petroleum Bureau General Hospital, Hebei Medical University, No. 8 Huizhan Avenue, Renqiu 062552, Hebei Province, China. billhappy001@163.com
Received: December 21, 2023
Revised: May 10, 2024
Accepted: May 20, 2024
Published online: August 15, 2024
Processing time: 231 Days and 2.5 Hours
Abstract

Laparoscopic surgery is the main treatment method for patients with gastrointestinal malignant tumors. Although laparoscopic surgery is minimally invasive, its tool stimulation and pneumoperitoneum pressure often cause strong stress reactions in patients. On the other hand, gastrointestinal surgery can cause stronger pain in patients, compared to other surgeries. Transversus abdominis plane block (TAPB) can effectively inhibit the transmission of nerve impulses caused by surgical stimulation, alleviate patient pain, and thus alleviate stress reactions. Remazolam is an acting, safe, and effective sedative, which has little effect on hemodynamics and is suitable for most patients. TAPB combined with remazolam can reduce the dosage of total anesthetic drugs, reduce adverse reactions, reduce stress reactions, and facilitate the rapid postoperative recovery of patients.

Keywords: Transversus abdominis plane block; Remazolam; Hemodynamics; Gastrointestinal tumor surgery; Oxidative stress

Core Tip: The application of laparoscopy in gastrointestinal tumor surgery can lead to strong stress reactions, severe changes in hemodynamics, and an increased risk of postoperative adverse events. The application of transversus abdominis plane block, combined with remazolam, to treat laparoscopic tumor patients can promote more stable anesthesia, reduce hemodynamic fluctuations, and improve the quality of patient rehabilitation.