Published online Mar 15, 2024. doi: 10.4251/wjgo.v16.i3.653
Peer-review started: December 21, 2023
First decision: January 10, 2024
Revised: January 15, 2024
Accepted: February 6, 2024
Article in press: February 6, 2024
Published online: March 15, 2024
Processing time: 82 Days and 1.6 Hours
Pylorus-preserving gastrectomy (PPG) has been widely accepted as a function-preserving gastrectomy for middle-third early gastric cancer (EGC) with a distal tumor border at least 4 cm proximal to the pylorus. The procedure essentially preserves the function of the pyloric sphincter, which requires to preserve the upper third of the stomach and a pyloric cuff at least 2.5 cm. The suprapyloric and infrapyloric vessels are usually preserved, as are the hepatic and pyloric branches of the vagus nerve. Compared with distal gastrectomy, PPG has significant advantages in preventing dumping syndrome, body weight loss and bile reflux gastritis. The postoperative complications after PPG have reached an acceptable level. PPG can be considered a safe, effective, and superior choice in EGC, and is expected to be extensively performed in the future.
Core Tip: Pylorus-preserving gastrectomy (PPG) has been widely accepted as a function-preserving gastrectomy for middle-third early gastric cancer. The procedure requires to preserve the upper third of the stomach and a pyloric cuff at least 2.5 cm. The hepatic and pyloric branches of the vagus nerve are usually preserved. PPG has significant advantages in preventing dumping syndrome, body weight loss and bile reflux gastritis.