Exosomes: Promising biomarkers and targets for cancer

doi:10.4251/wjgo.v14.i8.1594

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World Journal of Gastrointestinal Oncology

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1948-5204

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Letter to the Editor

World J Gastrointest Oncol. Aug 15, 2022; 14(8): 1594-1596
Published online Aug 15, 2022. doi: 10.4251/wjgo.v14.i8.1594

Exosomes: Promising biomarkers and targets for cancer

Zhen Fang, Yi-Xuan Ding, Fei Li

Zhen Fang, Yi-Xuan Ding, Fei Li, Department of General Surgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China

Author contributions: Fang Z and Ding YX wrote the manuscript; Li F designed the study; and All authors have read and approve the final manuscript.

Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.

Corresponding author: Zhen Fang, PhD, Academic Research, Surgeon, Department of General Surgery, Xuanwu Hospital of Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. ifang123@163.com

Received: February 17, 2022
Peer-review started: February 17, 2022
First decision: April 17, 2022
Revised: April 25, 2022
Accepted: July 19, 2022
Article in press: July 19, 2022
Published online: August 15, 2022
Processing time: 174 Days and 4.6 Hours

Abstract

The review article entitled "Exosomes as potential diagnosis and treatment for liver cancer " recently published in World Journal of Gastrointestinal Oncology 2022; 14: 334-347 concluded that exosomes can be used as effective biomarkers or therapeutic biotargets in liver cancer. Exosomes are a hot spot in the field of tumor diagnosis and treatment research. We had also previously published a review on exosomes and tumors. In this letter to the editor, we summarize the clinical application prospects and current challenges of exosomes.

Keywords: Exosomes; Cancer; Biomarkers; Diagnosis; Therapy

Core Tip: Exosomes have been shown to be major transmitters of cell-to-cell communication. Several advantageous features make exosomes effective therapeutic targets for cancer and ideal vehicles for drug delivery. This letter highlights the opportunities and challenges for clinical study and application of exosomes.