Prevention of late complications of endoscopic resection of colorectal lesions with a coverage agent: Current status of gastrointestinal endoscopy

doi:10.4251/wjgo.v14.i2.543

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 14, Issue 2

This Article

Academic Content and Language Evaluation of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (4726)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series.

Item

Count

PDF

272

WORD

123

HTML

2111

Figures (1-1)

573

Sum=3079

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

472

Download

1175

Sum=1647

Feb 15, 2022 (publication date) through Feb 11, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Oncology

ISSN

1948-5204

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Letter to the Editor

World J Gastrointest Oncol. Feb 15, 2022; 14(2): 543-546
Published online Feb 15, 2022. doi: 10.4251/wjgo.v14.i2.543

Prevention of late complications of endoscopic resection of colorectal lesions with a coverage agent: Current status of gastrointestinal endoscopy

Yan-Dong Miao, Xiao-Long Tang, Jiang-Tao Wang, Deng-Hai Mi

Yan-Dong Miao, Xiao-Long Tang, Jiang-Tao Wang, Deng-Hai Mi, The First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China

Deng-Hai Mi, Dean's office, Gansu Academy of Traditional Chinese Medicine, Lanzhou 730000, Gansu Province, China

Author contributions: Mi DH and Miao YD designed the research; Miao YD wrote this comment; Tang XL and Wang JT made academic advice; Mi DH reviewed this manuscript; and all authors approved the final manuscript.

Conflict-of-interest statement: No conflict of interest associated with any of the senior authors or other coauthors contributed their efforts in this manuscript.

Corresponding author: Deng-Hai Mi, MD, Chief Doctor, Dean, The First Clinical Medical College, Lanzhou University, No. 1 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. mi.dh@outlook.com

Received: June 23, 2021
Peer-review started: June 23, 2021
First decision: July 29, 2021
Revised: July 31, 2021
Accepted: January 25, 2022
Article in press: January 25, 2022
Published online: February 15, 2022
Processing time: 231 Days and 21 Hours

Abstract

Endoscopic ectomy of large nonpedunculated colorectal lesions (≥ 20 mm) might cause significant adverse incidents, such as delayed perforation and delayed bleeding, despite the closure of mucosal lesions with clips. The conventional utilization of prophylactic clipping has not decreased the risk of postprocedural delayed adverse events, and additional outcomes and cost-effectiveness research is needed for patients with proximal lesions ≥ 20 mm, in whom prophylactic clipping might be useful. Coverage of the wound after endoscopic excision offers shield protection against delayed concomitant diseases.

Keywords: Endoscopic resection; Non-pedunculated colorectal lesions; Complication; Delayed bleeding; Delayed perforation; Coverage agents

Core Tip: The conventional application of prophylactic clipping has not diminished overall risk of postprocedural delayed adverse events, and additional efficacy and cost-effectiveness studies are needed in patients with large (20 mm) non-pedunculated colorectal lesions, in whom prophylactic clipping may be useful. The preventive process significantly decreases the risk of delayed adverse events (delayed bleeding and delayed perforation) by more than 80%.