Use of liquid biopsies in gastrointestinal cancers

doi:10.4251/wjgo.v13.i9.1210

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World Journal of Gastrointestinal Oncology

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1948-5204

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Letter to the Editor

World J Gastrointest Oncol. Sep 15, 2021; 13(9): 1210-1212
Published online Sep 15, 2021. doi: 10.4251/wjgo.v13.i9.1210

Use of liquid biopsies in gastrointestinal cancers

Hussein H Khachfe

Hussein H Khachfe, Department of Gastrointestinal Surgical Oncology, University of Pittsburgh, Pittsburgh, PA 15232, United States

Author contributions: Khachfe HH performed the research, wrote, and revised the letter.

Conflict-of-interest statement: The author does not report any conflict of interest. The author did not receive any funding.

Corresponding author: Hussein H Khachfe, MD, Doctor, Research Fellow, Department of Gastrointestinal Surgical Oncology, University of Pittsburgh, 3550 Terrace St, Pittsburgh, PA 15232, United States. hhk15@mail.aub.edu

Received: May 8, 2021
Peer-review started: May 8, 2021
First decision: June 16, 2021
Revised: June 16, 2021
Accepted: August 9, 2021
Article in press: August 9, 2021
Published online: September 15, 2021
Processing time: 124 Days and 20.6 Hours

Abstract

The use of liquid biopsies is a relatively new tool in diagnosis and management of gastrointestinal cancers and is actively being investigated. Liquid biopsies have become extremely popular in cholangiocarcinoma and pancreatic cancer research. With more prospective trials using this tool for early diagnosis, liquid biopsies may become an important part of cancer management.

Keywords: Liquid biopsy; Gastrointestinal cancer; Cholangiocarcinoma; Pancreatic cancer

Core Tip: Liquid biopsies are a novel method to help physicians in the early diagnosis and management of various cancer subtypes. Due to the east of performance, cost-effectiveness, and quick results associated with liquid biopsies, this technique will be integrated more into the treatment of aggressive cancer types such as cholangiocarcinoma and pancreatic cancers. More prospective clinical trials are needed to validate results on this tool.