Yorita K, Iwasaki T, Uchita K, Kuroda N, Kojima K, Iwamura S, Tsutsumi Y, Ohno A, Kataoka H. Russell body gastritis with Dutcher bodies evaluated using magnification endoscopy. World J Gastrointest Endosc 2017; 9(8): 417-424 [PMID: 28874963 DOI: 10.4253/wjge.v9.i8.417]
Corresponding Author of This Article
Kenji Yorita, MD, PhD, Department of Diagnostic Pathology, Japanese Red Cross Kochi Hospital, 2-13-51, Shinhonmachi, Kochi-city, Kochi 780-8562, Japan. kenjiyorita@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
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Yorita K, Iwasaki T, Uchita K, Kuroda N, Kojima K, Iwamura S, Tsutsumi Y, Ohno A, Kataoka H. Russell body gastritis with Dutcher bodies evaluated using magnification endoscopy. World J Gastrointest Endosc 2017; 9(8): 417-424 [PMID: 28874963 DOI: 10.4253/wjge.v9.i8.417]
Kenji Yorita, Naoto Kuroda, Department of Diagnostic Pathology, Japanese Red Cross Kochi Hospital, Kochi-city, Kochi 780-8562, Japan
Takehiro Iwasaki, Kunihisa Uchita, Koji Kojima, Shinichi Iwamura, Department of Internal Medicine, Japanese Red Cross Kochi Hospital, Kochi-city, Kochi 780-8562, Japan
Yutaka Tsutsumi, Department of Pathology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
Akinobu Ohno, Pathology Section, University of Miyazaki Hospital, Miyazaki 889-1601, Japan
Hiroaki Kataoka, Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1601, Japan
Author contributions: Yorita K performed pathological diagnosis, collected and analyzed the data, and wrote the paper; Iwasaki T, Uchita K, Kojima K and Iwamura S performed the clinical diagnosis, endoscopic submucosal resection of the lesion, and clinical follow-up; Kuroda N, Tsutsumi Y, Ohno A and Kataoka H performed the pathological diagnosis.
Institutional review board statement: This case report was approved by the institutional review board of the Japanese Red Cross Kochi Hospital.
Informed consent statement: The patient described in this case report provided written informed consent.
Conflict-of-interest statement: All the authors have no conflicts of interests to declare.
Correspondence to: Kenji Yorita, MD, PhD, Department of Diagnostic Pathology, Japanese Red Cross Kochi Hospital, 2-13-51, Shinhonmachi, Kochi-city, Kochi 780-8562, Japan. kenjiyorita@gmail.com
Telephone: +81-88-8221201 Fax: +81-88-8221056
Received: November 29, 2016 Peer-review started: December 1, 2016 First decision: February 20, 2017 Revised: March 13, 2017 Accepted: April 23, 2017 Article in press: April 24, 2017 Published online: August 16, 2017 Processing time: 254 Days and 14 Hours
Core Tip
Core tip: We report Russell body gastritis (RBG) evaluated by magnification endoscopy with narrow band imaging and pathological evaluation by endoscopic submucosal dissection. The endoscopic features of RBG are exclusively inflammatory; however, our detailed endoscopic evaluation led to misdiagnosis of the lesion as poorly differentiated adenocarcinoma. The histological features of RBG were also unique because the presence of Mott cells with light chain restriction and Dutcher bodies suggested malignant lymphoma. Pathologists should be aware of the existence of this pathological entity, and clinicians should consider RBG as a differential diagnosis in cases where detailed endoscopic examination reveals poorly differentiated early gastric cancer.
