Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Endosc. Apr 16, 2026; 18(4): 118313
Published online Apr 16, 2026. doi: 10.4253/wjge.v18.i4.118313
Published online Apr 16, 2026. doi: 10.4253/wjge.v18.i4.118313
Letter to the Editor: Endoscopic ultrasound-guided liver biopsy for parenchymal disease: Feasibility, safety, and future considerations
Lian-Bang Wang, Xi-Ming Wang, Xin-Ya Zhao, Gong-Zheng Wang, Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Co-corresponding authors: Xin-Ya Zhao and Gong-Zheng Wang.
Author contributions: Wang LB wrote the original draft; Wang XM and Wang GZ participated in drafting the manuscript; Zhao XY and Wang GZ contributed to conceptualization, writing, reviewing, and editing as co-corresponding authors; all authors have read and approved the final version of the manuscript.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Corresponding author: Gong-Zheng Wang, PhD, Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan 250021, Shandong Province, China. wanggz0322@163.com
Received: December 29, 2025
Revised: January 18, 2026
Accepted: February 14, 2026
Published online: April 16, 2026
Processing time: 105 Days and 16.3 Hours
Revised: January 18, 2026
Accepted: February 14, 2026
Published online: April 16, 2026
Processing time: 105 Days and 16.3 Hours
Core Tip
Core Tip: Endoscopic ultrasound-guided liver biopsy is an established alternative to percutaneous biopsy for parenchymal liver disease. Alali et al report high diagnostic adequacy and a low rate of serious adverse events, reinforcing existing evidence of safety and effectiveness. Their findings suggest that the use of a 19-gauge core biopsy needle and wet heparin suction improves specimen quality. However, the retrospective design and limited sample size warrant cautious interpretation, and larger prospective studies are needed to confirm these observations and refine optimal biopsy techniques.