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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2026; 18(2): 113762
Published online Feb 16, 2026. doi: 10.4253/wjge.v18.i2.113762
Published online Feb 16, 2026. doi: 10.4253/wjge.v18.i2.113762
Bowel preparation for small bowel capsule endoscopy in patients with suspected or established Crohn’s disease
Shohei Terashi, Sotaro Ozaka, Yomei Kagoshima, Yuta Shimomori, Haruhiko Takahashi, Daisuke Minezaki, Koshiro Tsutsumi, Masahide Fukuda, Yuka Hirashita, Kensuke Fukuda, Ryo Ogawa, Masaaki Kodama, Kazunari Murakami, Kazuhiro Mizukami, Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu 879-5593, Japan
Sotaro Ozaka, Yomei Kagoshima, Department of Infectious Disease Control, Faculty of Medicine, Oita University, Yufu 879-5593, Japan
Co-corresponding authors: Sotaro Ozaka and Kazuhiro Mizukami.
Author contributions: Ozaka S and Mizukami K contributed equally to this manuscript and are co-corresponding authors. Terashi S and Ozaka S developed the study design and wrote the manuscript; Shimomori Y, Kagoshima Y, Takahashi H, Minezaki D, Tsutsumi K, Fukuda M, Hirashita Y, Fukuda K, and Ogawa R performed the small-bowel capsule endoscopy and acquired the data; Ozaka S and Mizukami K reviewed and corrected the manuscript; Murakami K, Kodama M, and Ozaka S provided oversight for the manuscript and revised it for important intellectual content; all authors issued final approval for the version to be submitted.
Supported by Takeda Science Foundation, No. 2025045981.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Oita University Faculty of Medicine, No. 3144.
Informed consent statement: Written informed consent was obtained from each patient before small-bowel capsule endoscopy examination. The authors declare that the study consisted of a retrospective assessment and was conducted in accordance with the Declaration of Helsinki.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sotaro Ozaka, MD, PhD, Assistant Professor, Department of Gastroenterology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama, Yufu 879-5593, Japan. ozakaso@oita-u.ac.jp
Received: September 3, 2025
Revised: September 27, 2025
Accepted: December 10, 2025
Published online: February 16, 2026
Processing time: 154 Days and 20.5 Hours
Revised: September 27, 2025
Accepted: December 10, 2025
Published online: February 16, 2026
Processing time: 154 Days and 20.5 Hours
Core Tip
Core Tip: Small-bowel capsule endoscopy (SBCE) is an important tool in the diagnosis of Crohn’s disease (CD). The necessity and consensus protocol of preprocedural bowel pre-treatment for SBCE in patients with CD have not been established. This study aimed to describe the contribution of preprocedural bowel preparation in SBCE for patients with CD with small intestinal lesions by comparing the diagnostic performance and mucosal visibility. We believe that our study makes a significant contribution to the literature because it showed that the diagnostic performance and mucosal visibility of small-bowel capsule endoscopy for CD were not significantly improved by pre-procedural bowel preparation.