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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jan 16, 2026; 18(1): 112920
Published online Jan 16, 2026. doi: 10.4253/wjge.v18.i1.112920
Published online Jan 16, 2026. doi: 10.4253/wjge.v18.i1.112920
Purastat therapy for bleeding radiation proctopathy
Jervoise Andreyev, Department of Gastroenterology, Lincoln County Hospital, Lincoln LN2 5QY, Lincolnshire, United Kingdom
Author contributions: Andreyev J contributed to designed, conducted, analysed and wrote the study.
Conflict-of-interest statement: The author declare that he received Purastat without charge from the manufacturers to treat the patients enrolled in this study but has no other conflict of interest to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jervoise Andreyev, Consultant, Department of Gastroenterology, Lincoln County Hospital, Greetwell Road, Lincoln LN2 5QY, Lincolnshire, United Kingdom. jervoiseandreyev@gmail.com
Received: August 11, 2025
Revised: August 31, 2025
Accepted: December 19, 2025
Published online: January 16, 2026
Processing time: 159 Days and 4 Hours
Revised: August 31, 2025
Accepted: December 19, 2025
Published online: January 16, 2026
Processing time: 159 Days and 4 Hours
Core Tip
Core Tip: New data on the effectiveness of Purastat. There are limited data as to the effectiveness of Purastat to treat bleeding radiation proctopathy. Purastat reduced bleeding and improved nuisance scores in 11 patients with severely symptomatic ble