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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2025; 17(9): 109396
Published online Sep 16, 2025. doi: 10.4253/wjge.v17.i9.109396
Published online Sep 16, 2025. doi: 10.4253/wjge.v17.i9.109396
Unsuspected efficacy of starch-based polysaccharide vs crystalloid-oil emulsion for lifting in colonic endoscopic resections
Sartajdeep Kahlon, Amer Alsamman, Jiten Desai, Shiro Urayama, Division of Gastroenterology and Hepatology, Department of Internal Medicine, UC Davis Medical Center, Sacramento, CA 95817, United States
Author contributions: Kahlon S, Alsamman A, and Desai J were responsible for data collection and analysis; Kahlon S and Urayama S were responsible for conception and design; Kahlon S, Alsamman A, Desai J, and Urayama S were responsible for writing and editing; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and determined to be exempt by the UC Davis Institutional Review Board (No. 1982596-1) on November 22, 2022, under category Exempt 4(iii), flex.
Informed consent statement: Patient consent was waived by the Institutional Review Board, as the research met the criteria for minimal risk and involved retrospective data collection only, consistent with Health Insurance Portability and Accountability Act regulations.
Conflict-of-interest statement: The authors declare no conflicts of interest relevant to this study.
Data sharing statement: The data supporting the findings of this study are not publicly available due to privacy and institutional restrictions. Reasonable requests for access to de-identified data may be considered by the corresponding author, in compliance with institutional and Institutional Review Board guidelines.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shiro Urayama, MD, Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, UC Davis Medical Center, 4150 V Street Suite 3500, Sacramento, CA 95817, United States. surayama@ucdavis.edu
Received: May 12, 2025
Revised: May 30, 2025
Accepted: August 20, 2025
Published online: September 16, 2025
Processing time: 125 Days and 12 Hours
Revised: May 30, 2025
Accepted: August 20, 2025
Published online: September 16, 2025
Processing time: 125 Days and 12 Hours
Core Tip
Core Tip: This retrospective study compares starch-based polysaccharide solution (SPS) and crystalloid-oil emulsion solution (COES) as submucosal lifting agents in colonic endoscopic mucosal resection and endoscopic submucosal dissection. SPS use was associated with shorter procedure times, significantly less intraprocedural bleeding, fewer adverse events, and higher en bloc resection rates compared to COES. These findings support the potential dual role of SPS as both an effective lifting and hemostatic agent.