Retrospective Cohort Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jun 16, 2025; 17(6): 103183
Published online Jun 16, 2025. doi: 10.4253/wjge.v17.i6.103183
Long-term outcomes of post-transplant biliary anastomotic strictures: Endoscopic therapy with plastic and metal stents
Larissa Wermelinger Pinheiro, Fernanda Prata Martins, Angelo Paulo Ferrari, Edmar Tafner, Gustavo Andrade De Paulo, Ermelindo Della Libera
Larissa Wermelinger Pinheiro, Angelo Paulo Ferrari, Ermelindo Della Libera, Gastroenterology Division of Escola Paulista de Medicina, São Paulo Federal University, São Paulo 04039-032, Brazil
Fernanda Prata Martins, Angelo Paulo Ferrari, Edmar Tafner, Gustavo Andrade De Paulo, Ermelindo Della Libera, Digestive Endoscopy Unit, Hospital Israelita Albert Einstein, São Paulo 05652-900, Brazil
Author contributions: Pinheiro LW was responsible for data acquisition, analysis and interpretation, and elaboration of article draft; Martins FP and Tafner E were responsible for data acquisition, elaboration and review of the article draft, and reviewing critically for important intellectual content; De Paulo GA was responsible for data acquisition, analysis and interpretation, and critical review of the final paper for important intellectual content; Ferrari AP and Libera ED were responsible for data analysis and interpretation, critical review, and approval of the final submitted version; All authors read and approved the final version of the manuscript to be published.
Institutional review board statement: This study was approved by the Ethics Committee of the Israelita Albert Einstein Hospital.
Informed consent statement: Patients were required to provide informed consent to the study according to the requirements of the committee of the Israelita Albert Einstein Hospital.
Conflict-of-interest statement: The authors have no conflicting relationships to disclose.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ermelindo Della Libera, MD, PhD, Gastroenterology Division of Escola Paulista de Medicina, São Paulo Federal University, Rua Pedro de Toledo, 861/869-Vila Clementino, São Paulo 04039-032, Brazil. edellaliberajr@uol.com.br
Received: November 11, 2024
Revised: April 1, 2025
Accepted: May 18, 2025
Published online: June 16, 2025
Processing time: 212 Days and 6.7 Hours
Core Tip

Core Tip: This retrospective study evaluated the resolution and recurrence of endoscopic treatment using multiple plastic stents (MPSs) and covered self-expandable metal stents (cSEMSs) in patients with post-orthotopic liver transplantation (OLT) biliary anastomotic stricture. Patients were stratified into two groups according to therapy: (1) MPSs; and (2) cSEMSs. Stricture resolution occurred in 101/104 patients (97.1%). Adverse events occurred in 48% in the cSEMS group and 10% in the MPS group. The cSEMSs and MPSs were effective and comparable regarding biliary anastomotic strictures post-OLT.