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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 16, 2025; 17(12): 110432
Published online Dec 16, 2025. doi: 10.4253/wjge.v17.i12.110432
Published online Dec 16, 2025. doi: 10.4253/wjge.v17.i12.110432
Endoscopic treatment of malignant hilar biliary obstruction: A retrospective cohort study
Jakub Pietrzak, Jan Pertkiewicz, Sławomir Kozieł, Paweł Babski, Joanna Ligocka, Adam Przybyłkowski, Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, Warsaw 02-091, Mazowieckie, Poland
Author contributions: Pietrzak J conceived the study and designed the methodology; Pietrzak J, Ligocka J, Pertkiewicz J, Kozieł S, and Babski P performed the endoscopic procedures; Pietrzak J collected and analyzed the data and drafted the manuscript; Przybyłkowski A conducted the critical review and revised the manuscript; all authors participated in the final review, approved the manuscript, and ensured the accuracy and integrity of the work.
Institutional review board statement: The study was submitted to the Bioethics Committee of the Medical University of Warsaw, which confirmed that formal approval was not required due to the retrospective design and full anonymization of patient data. The study was conducted in accordance with institutional and national ethical standards and with the 1964 Helsinki Declaration and its later amendments.
Informed consent statement: Informed consent was waived due to the retrospective nature of the study and the use of fully anonymized data, as approved by the institutional bioethics committee.
Conflict-of-interest statement: The authors declare no conflicts of interest related to this study. No financial or non-financial support from any commercial entity was received.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: The anonymized datasets used and analyzed during the current study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Adam Przybyłkowski, Full Professor, Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, 1a Banacha Street, Warsaw 02-091, Mazowieckie, Poland. aprzybylkowski@wum.edu.pl
Received: June 7, 2025
Revised: July 12, 2025
Accepted: October 17, 2025
Published online: December 16, 2025
Processing time: 193 Days and 9.3 Hours
Revised: July 12, 2025
Accepted: October 17, 2025
Published online: December 16, 2025
Processing time: 193 Days and 9.3 Hours
Core Tip
Core Tip: This retrospective cohort study analyzed 164 patients with malignant hilar biliary obstruction (MHBO) treated through endoscopic intervention using different stent types and drainage strategies. Uncovered self-expandable metal stents were associated with the longest survival and stent patency. Adjunctive therapies such as radiofrequency ablation and chem