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World J Gastrointest Endosc. Nov 16, 2025; 17(11): 112519
Published online Nov 16, 2025. doi: 10.4253/wjge.v17.i11.112519
Brief overview of congenital gastric ectopic pylorus: A rare gastric abnormality
Chang Wang, Chen-Huan Wang, Wen-Ju Shi, Sheng-Wu Pan, Ya-Qi Zhai
Chang Wang, Sheng-Wu Pan, Department of Gastroenterology, People’s Liberation Army Joint Logistic Support Force 985th Hospital, Taiyuan 030001, Shanxi Province, China
Chen-Huan Wang, Ya-Qi Zhai, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
Wen-Ju Shi, Office of Hospital Administration, People’s Liberation Army Joint Logistic Support Force 985th Hospital, Taiyuan 030001, Shanxi Province, China
Co-first authors: Chang Wang and Chen-Huan Wang.
Author contributions: Wang C and Wang CH drafted the manuscript; Wang C and Zhai YQ conceived and designed the study, conducted literature search, data collection; Shi WJ and Pan SW verified the data and prepared the figures and tables; Zhai YQ revised the manuscript; Wang C and Wang CH contributed equally to this work, and are co-first authors of this article. All authors have read and approved the final version.
Supported by National Key Research and Development Project, No. 2022YFC2503603; and 985th Hospital Research Project, No. YN202405.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ya-Qi Zhai, MD, PhD, Associate Professor, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese People’s Liberation Army General Hospital, No. 28 Fuxing Road, Beijing 100853, China. astaring@163.com
Received: July 30, 2025
Revised: August 30, 2025
Accepted: October 22, 2025
Published online: November 16, 2025
Processing time: 107 Days and 23.8 Hours
Core Tip

Core Tip: Congenital gastric ectopic pylorus is an extremely rare congenital gastrointestinal anomaly characterized by an abnormal pyloric opening location. To date, only a few cases have been reported. This is the first review of congenital gastric ectopic pylorus regarding its history, etiology, diagnosis, and treatment, aiming to facilitate a better understanding of this rare condition.