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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Oct 16, 2025; 17(10): 107984
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.107984
Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.107984
Gallstones and common bile duct stones management: Single-stage vs two-stage treatment
Adriano Lauri, Lucia Cocomello, Stefano Fabiani, Giacomo Rando, Department of Gastro
Gaetano Lauri, Department of Pancreato-Biliary Endoscopy and Endosonography, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Milan 20132, Lombardy, Italy
Co-first authors: Adriano Lauri and Lucia Cocomello.
Author contributions: Lauri A designed the study outline and coordinated the preparation and revision of the manuscript; Cocomello L performed the majority of the writing and literature analysis; Fabiani S and Rando G provided critical revisions, conceptual input, and prepared the figures and tables; Lauri G contributed to data collection and drafting of the manuscript. Lauri A and Cocomello L contributed equally to this manuscript and are co-first authors. All authors read and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gaetano Lauri, MD, Consultant, Department of Pancreato-Biliary Endoscopy and Endosonography, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Lombardy, Italy.
Received: April 2, 2025
Revised: June 9, 2025
Accepted: September 19, 2025
Published online: October 16, 2025
Processing time: 197 Days and 10.8 Hours
Revised: June 9, 2025
Accepted: September 19, 2025
Published online: October 16, 2025
Processing time: 197 Days and 10.8 Hours
Core Tip
Core Tip: The conventional two-stage approach separates endoscopic and surgical interventions, whereas the single-stage laparoendoscopic rendezvous procedure provides a more streamlined alternative. This study highlights the advantages of laparoendoscopic rendezvous, including shorter hospital stay, a reduced risk of post-endoscopic retrograde cholangiopancreatography pancreatitis, and improved bile duct clearance. Furthermore, we examine its feasibility across various healthcare settings, particularly in low-volume centers, where procedural consolidation could enhance outcomes. Future studies should focus on refining patient selection and evaluating long-term benefits to optimize clinical practice.