Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2021; 13(5): 155-160
Published online May 16, 2021. doi: 10.4253/wjge.v13.i5.155
Peroral endoscopic myotomy in a pregnant woman diagnosed with mitochondrial disease: A case report
Alexander A Smirnov, Maya M Kiriltseva, Mariya E Lyubchenko, Vladimir D Nazarov, Anna V Botina, Aleksandr N Burakov, Sergey V Lapin
Alexander A Smirnov, Maya M Kiriltseva, Mariya E Lyubchenko, Aleksandr N Burakov, Department of Endoscopy, Pavlov First Saint Petersburg State Medical University, Saint Petersburg 197022, Russia
Vladimir D Nazarov, Sergey V Lapin, Center for Molecular Medicine, Pavlov First Saint Petersburg State Medical University, Saint Petersburg 197022, Russia
Anna V Botina, Department of Pathology, Pavlov First Saint Petersburg State Medical University, Saint Petersburg 197022, Russia
Author contributions: Smirnov AA and Lyubchenko ME performed peroral endoscopic myotomy, reviewed the literature and contributed to manuscript drafting; Kiriltseva MM performed the gastroenterology consultation; Burakov AN and Kiriltseva MM reviewed the literature and contributed to manuscript drafting; Nazarov VD and Lapin SV performed the genetic tests and interpretation and contributed to manuscript drafting; Botina AV provided the histology report; Burakov AN and Kiriltseva MM were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Aleksandr N Burakov, Research Fellow, Department of Endoscopy, Pavlov First Saint Petersburg State Medical University, L’va Tolstogo Str. 6-8, Saint Petersburg 197022, Russia. aleksandr.medox@yandex.ru
Received: December 19, 2020
Peer-review started: December 19, 2020
First decision: February 15, 2021
Revised: March 6, 2021
Accepted: April 26, 2021
Article in press: April 26, 2021
Published online: May 16, 2021
Processing time: 131 Days and 7.7 Hours
Core Tip

Core Tip: Achalasia is a primary esophageal motility disease. Sometimes is can be a part of some genetic disorders. One of the causes of gastrointestinal motility disorders, including achalasia, is mitochondrial defects. We report about a pregnant woman with a history of symptoms associated with inherited mitochondrial disease, which was confirmed by genetic tests, and who was successfully treated via peroral endoscopic myotomy.