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Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2018; 10(9): 145-155
Published online Sep 16, 2018. doi: 10.4253/wjge.v10.i9.145
Clinical update on the management of pseudopapillary tumor of pancreas
Gandhi Lanke, Faisal S Ali, Jeffrey H Lee
Gandhi Lanke, Faisal S Ali, Jeffrey H Lee, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States
Author contributions: Lanke G composed and drafted the paper; Ali SF provided the figures and edited the paper; Lee JH provided outlines, reviewed and edited the paper.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jeffrey H Lee, MD, Professor, Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, United States. jefflee@mdanderson.org
Telephone: +1-713-7945073 Fax: +1-713-5634408
Received: March 14, 2018
Peer-review started: March 14, 2018
First decision: April 23, 2018
Revised: April 28, 2018
Accepted: June 8, 2018
Article in press: June 9, 2018
Published online: September 16, 2018
Processing time: 187 Days and 2.5 Hours
Core Tip

Core tip: Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. SPNs are usually indolent but they do have malignant potential. The pathogenesis of SPN is not entirely clear. Accurate diagnosis is essential in the management of SPN. Endoscopic ultrasound guided fine needle aspiration with immunohistochemistry can help distinguish SPNs from other aggressive pancreatic tumors preoperatively. Surgical resection with clear margins is curative and should be offered whenever feasible. The prognosis of SPN is good even in the presence of metastasis.